Results 71 to 80 of about 1,535,774 (186)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Frontiers in Pigment Cell and Melanoma Research

open access: yes, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca   +26 more
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Cell Biology Redux

open access: yesMolecular Biology of the Cell, 2010
I came to cell biology from genetics because I found myself interested in understanding how things worked, not just why they worked. Although genetics is the most logical of all branches of biology, in the end, genes are merely placeholders for the complex choreography played out by the proteins, lipids, carbohydrates, and nucleic acids constituting a ...
openaire   +4 more sources

Visualisation of the information resources for cell biology [PDF]

open access: yes, 2005
Intelligent multimodal interfaces can facilitate scientists in utilising available information resources. Combining scientific visualisations with interactive and intelligent tools can help create a “habitable” information space.
Malchanau, Andrei   +2 more
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

An Overview Of Cell Biology

open access: yes, 2015
The presentation comprises an overview of Cell & Molecular Biology for Undergraduate students of Indian Universities.
openaire   +2 more sources

An Award for Cell Biology [PDF]

open access: yesThe Journal of Cell Biology, 1999
This remark, made by Gunter Blobel on American television after winning the 1999 Nobel Prize for Physiology or Medicine, was hardly uncharacteristic: the six-foot, snowy-haired Rockefeller University professor was typically, generously, extending his prize to all of us who toil 'midst ...
openaire   +5 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

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