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Biosystems, 1986
Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
L, Alberghina, L, Mariani, E, Martegani
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Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
L, Alberghina, L, Mariani, E, Martegani
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Nature Reviews Cancer, 2021
Oren et al. developed a lentiviral barcode library, called Watermelon, to characterize the rare population of cycling persister cancer cells that arise during the course of drug treatment and promote tumour relapse.
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Oren et al. developed a lentiviral barcode library, called Watermelon, to characterize the rare population of cycling persister cancer cells that arise during the course of drug treatment and promote tumour relapse.
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Cytometry, 1991
AbstractTechniques for the measurement of bromodeoxyuridine (BrdUrd) positive cells generally include either microscopic evaluation of paraffin embedded sections or measurements on cell suspensions using a fluorescent activated cell sorter. The accuracy of these measurements and their correlations can be affected by a number of technical and intrinsic ...
S, Kaleta-Michaels +3 more
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AbstractTechniques for the measurement of bromodeoxyuridine (BrdUrd) positive cells generally include either microscopic evaluation of paraffin embedded sections or measurements on cell suspensions using a fluorescent activated cell sorter. The accuracy of these measurements and their correlations can be affected by a number of technical and intrinsic ...
S, Kaleta-Michaels +3 more
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Science, 1996
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
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Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
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New England Journal of Medicine, 1981
FIFTEEN years ago it seemed that one could selectively damage cancer cells by exploiting simple differences in the cell-cycle kinetics of normal and neoplastic cells.
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FIFTEEN years ago it seemed that one could selectively damage cancer cells by exploiting simple differences in the cell-cycle kinetics of normal and neoplastic cells.
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Blood Reviews, 1991
Over the past few years there has been a resurgance of interest in the cell cycle. The excitement has mainly been due to the fact that researchers all over the world who had been working on seemingly different processes in yeast, fruit flies, frogs and man have found that many of the processes and individual proteins have been highly conserved.
A, Bybee, N S, Thomas
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Over the past few years there has been a resurgance of interest in the cell cycle. The excitement has mainly been due to the fact that researchers all over the world who had been working on seemingly different processes in yeast, fruit flies, frogs and man have found that many of the processes and individual proteins have been highly conserved.
A, Bybee, N S, Thomas
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2002
The cell cycle is the sequence of events through which a cell duplicates its genome, grows, and divides. Major cell cycle transitions are driven by cyclin-dependent kinases and other kinases. Ubiquitin-mediated protein degradation is also a major driving force for cell cycle transitions.
V J, Tannoch, P W, Hinds, L H, Tsai
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The cell cycle is the sequence of events through which a cell duplicates its genome, grows, and divides. Major cell cycle transitions are driven by cyclin-dependent kinases and other kinases. Ubiquitin-mediated protein degradation is also a major driving force for cell cycle transitions.
V J, Tannoch, P W, Hinds, L H, Tsai
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Current Opinion in Cell Biology, 1994
Checkpoints help ensure that cell cycle events occur in the correct order. Studies on mammalian cells identified inhibitors of complexes of cyclins and cyclin-dependent kinases as components of cell cycle checkpoints and provide the first glimpse of the molecular pathways that prevent cells with damaged DNA from replicating their DNA.
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Checkpoints help ensure that cell cycle events occur in the correct order. Studies on mammalian cells identified inhibitors of complexes of cyclins and cyclin-dependent kinases as components of cell cycle checkpoints and provide the first glimpse of the molecular pathways that prevent cells with damaged DNA from replicating their DNA.
openaire +2 more sources