Results 51 to 60 of about 15,811,009 (408)
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011 The control of cell proliferation by microRNAs (miRNAs) is well established and the alteration of these small, non-coding RNAs may contribute to tumor development by perturbing critical cell cycle regulators. Oncogenic miRNAs may facilitate cell cycle entry and progression by targeting CDK inhibitors or transcriptional repressors of the retinoblastoma ...
Marcos Malumbres, Maria J. Bueno
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Transcriptome changes and cAMP oscillations in an archaeal cell cycle [PDF]
, 2007 Background The cell cycle of all organisms includes mass increase by a factor of two, replication of the genetic material, segregation of the genome to different parts of the cell, and cell division into two daughter cells.
Baumann, Anke +2 more
core +3 more sources
Cell reprogramming modelled as transitions in a hierarchy of cell cycles [PDF]
J. Phys. A: Math. Theor. 50 (2017) 425601 (23pp), 2016 We construct a model of cell reprogramming (the conversion of fully differentiated cells to a state of pluripotency, known as induced pluripotent stem cells, or iPSCs) which builds on key elements of cell biology viz. cell cycles and cell lineages. Although reprogramming has been demonstrated experimentally, much of the underlying processes governing ...
arxiv +1 more source
The cell cycle and pluripotency [PDF]
Biochemical Journal, 2013 PSCs (pluripotent stem cells) possess two key properties that have made them the focus of global research efforts in regenerative medicine: they have unlimited expansion potential under conditions which favour their preservation as PSCs and they have the ability to generate all somatic cell types upon differentiation (pluripotency).
Anna Philpott, Christopher J. Hindley
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Evidence for an interplay between cell cycle progression and the initiation of differentiation between life cycle forms of African trypanosomes [PDF]
, 1994 Successful transmission of the African trypanosome between the mammalian host blood-stream and the tsetse fly vector involves dramatic alterations in the parasite's morphology and biochemistry.
Gull, K, Matthews, K R
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iScience, 2022 Summary: The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator.
Rodrigo Fraile +4 more
doaj
Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network [PDF]
, 2010 As in other eukaryotes, cell division in plants is highly conserved and regulated by cyclin-dependent kinases (CDKs) that are themselves predominantly regulated at the posttranscriptional level by their association with proteins such as cyclins. Although
Boruc, Joanna +8 more
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Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The spatial organization of RNAs within cells and spatial patterning of cells within tissues play crucial roles in many biological processes.
C. Xia +4 more
semanticscholar +1 more source
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d) [PDF]
, 2006 Calpains are a large family of Ca2+-dependent cysteine proteases that are ubiquitously distributed across most cell types and vertebrate species. Calpains play a role in cell differentiation, apoptosis, cytoskeletal remodeling, signal transduction and ...
Croall +13 more
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CDK control pathways integrate cell size and ploidy information to control cell division
eLife, 2021 Maintenance of cell size homeostasis is a property that is conserved throughout eukaryotes. Cell size homeostasis is brought about by the co-ordination of cell division with cell growth and requires restriction of smaller cells from undergoing mitosis ...
James Oliver Patterson +3 more
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