Results 91 to 100 of about 103,273 (243)

Transcriptomic correlates of cell cycle checkpoints with distinct prognosis, molecular characteristics, immunological regulation, and therapeutic response in colorectal adenocarcinoma. [PDF]

Front Immunol, 2023
Wang H, Wang W, Wang Z, Li X.
europepmc   +1 more source

Disrupt, Deny, Dismantle: A Special Operations Forces (SOF) Model for Combatting New Terrorism [PDF]

, 2016
Terrorism in the new millennium has morphed drastically since the 1970s. The terrorist organizations of today are a hybrid between the insurgent group models of the 1960s and modern terrorist organizations such as Al Qaeda.
Gunzelman, Will
core   +1 more source

DUBbing cancer: Deubiquitylating enzymes involved in epigenetics, DNA damage and the cell cycle as therapeutic targets

Frontiers in Genetics, 2016
Controlling cell proliferation is one of the hallmarks of cancer. A number of critical checkpoints ascertain progression through the different stages of the cell cycle, which can be aborted when perturbed, for instance by errors in DNA replication and ...
Benedikt M Kessler, Adán Pinto Fernández   +1 more
doaj   +1 more source

The Possible Crosstalk of MOB2 With NDR1/2 Kinases in Cell Cycle and DNA Damage Signaling [PDF]

, 2016
This article is the authors’ opinion of the roles of the signal transducer Mps one binder 2 (MOB2) in the control of cell cycle progression and the DNA Damage Response (DDR).
Hergovich, A
core   +1 more source

Supplemental Figure Legends from Coordinately Targeting Cell-Cycle Checkpoint Functions in Integrated Models of Pancreatic Cancer

, 2023
Sejin Chung, Paris Vail, Agnieszka K. Witkiewicz, Erik S. Knudsen   +3 more
openalex   +1 more source

Cell cycle checkpoints and beyond: Exploiting the ATR/CHK1/WEE1 pathway for the treatment of PARP inhibitor-resistant cancer. [PDF]

Pharmacol Res, 2022
Gupta N, Huang TT, Horibata S, Lee JM.
europepmc   +1 more source

Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage [PDF]

, 2017
Katarina Bačević, Gérald Lossaint, Thiziri Nait Achour, Virginie Georget, Daniel Fisher, Vjekoslav Dulić   +5 more
openalex   +1 more source

Coupling of the cell cycle and metabolism in yeast cell-cycle-related oscillations via resource criticality and checkpoint gating

Letters in Biomathematics, 2018
We investigate the possibility that slow metabolic, cell-cycle-related oscillations in yeast and associated temporal clustering of cells within the cell cycle could be due to an interplay between near-critical metabolism and cell cycle checkpoints.
Luke Morgan, Gregory Moses, Todd R. Young   +2 more
doaj   +1 more source

PLK1 Induces Chromosomal Instability and Overrides Cell-Cycle Checkpoints to Drive Tumorigenesis. [PDF]

Cancer Res, 2021
Gheghiani L, Wang L, Zhang Y, Moore XTR, Zhang J, Smith SC, Tian Y, Wang L, Turner K, Jackson-Cook CK, Mukhopadhyay ND, Fu Z.   +11 more
europepmc   +1 more source

Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints. [PDF]

Sci Rep, 2021
Hernansaiz-Ballesteros RD, Földi C, Cardelli L, Nagy LG, Csikász-Nagy A.   +4 more
europepmc   +1 more source