Results 81 to 90 of about 1,825,024 (378)

PAR proteins direct asymmetry of the cell cycle regulators Polo-like kinase and Cdc25 [PDF]

, 2008
Cell cycle lengths vary widely among different cells within an animal, yet mechanisms of cell cycle length regulation are poorly understood. In the Caenorhabditis elegans embryo, the first cell division produces two cells with different cell cycle ...
Abraham, Mary, Ahringer, Julie, Moreno, Sergio, Rivers, David M.   +3 more
core   +2 more sources

Expression of cell cycle proteins in male breast carcinoma

World Journal of Surgical Oncology, 2010
Introduction Male breast cancer (MBC) is a rare, yet potentially aggressive disease. Although literature regarding female breast cancer (FBC) is extensive, little is known about the etiopathogenesis of male breast cancer. Studies from our laboratory show
Senger Jenna-Lynn, Rueckl Theresa, Fried Isabella, Kanthan Rani, Kanthan Selliah   +4 more
doaj   +1 more source

A quantitative study of the division cycle of Caulobacter crescentus stalked cells. [PDF]

PLoS Computational Biology, 2008
Progression of a cell through the division cycle is tightly controlled at different steps to ensure the integrity of genome replication and partitioning to daughter cells. From published experimental evidence, we propose a molecular mechanism for control
Shenghua Li, Paul Brazhnik, Bruno Sobral, John J Tyson   +3 more
doaj   +1 more source

Gene Copy Number and Cell Cycle Arrest [PDF]

, 2005
The cell cycle is an orderly sequence of events which ultimately lead to the division of a single cell into two daughter cells. In the case of DNA damage by radiation or chemicals, the damage checkpoints in the $G_{1}$ and $G_{2}$ phases of the cell cycle are activated. This results in an arrest of the cell cycle so that the DNA damage can be repaired.
arxiv   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

FEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra, Paul Weiland, Pauline Anka Plitzko, Julia Thiery, Laura Czech, Felix Willmund, Patricia Bedrunka, Gert Bange   +7 more
wiley   +1 more source

Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation [PDF]

, 2013
Fascins, a family of actin-bundling proteins, are expressed in a spatially and temporally restricted manner during development and often in cancer.
Ackermann, Adams, Adams, Aratyn, Baxter, Borghese, Bravo-Cordero, Breitsprecher, Cant, Colombo, De Arcangelis, Delmas, Gillespie, Harris, Hashimoto, Hashimoto, Hashimoto, Hayashi, Hornyak, Jawhari, Jayo, Jayo, Jordan, Kim, Larue, Li, Li, Li, Lindsay, Loughna, Luciani, Machesky, Mackenzie, Migeotte, Mort, Nagy, Novak, Pelosi, Pla, Schoumacher, Sherr, Silver, Takemoto, Uyama, Vignjevic, Wang, Woolner, Xie, Xie, Yamakita, Yamakita, Yamashiro, Zanet   +52 more
core   +2 more sources

E3 Ubiquitin Ligase TRIM Proteins, Cell Cycle and Mitosis

Cells, 2019
The cell cycle is a series of events by which cellular components are accurately segregated into daughter cells, principally controlled by the oscillating activities of cyclin-dependent kinases (CDKs) and their co-activators.
Santina Venuto, Giuseppe Merla
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells

Journal of Experimental & Clinical Cancer Research, 2020
Background Our previous studies have confirmed that cobalt chloride (CoCl2) can induce the formation of polyploid giant cancer cells (PGCCs), which is the key to the heterogeneity of solid tumors.
Kai Liu, Minying Zheng, Qi Zhao, Kexin Zhang, Zugui Li, Fangmei Fu, Hao Zhang, Jiaxing Du, Yuwei Li, Shiwu Zhang   +9 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source