Results 11 to 20 of about 3,307,555 (359)
Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
, 2013 BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A +5 more
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Measurement and models accounting for cell death capture hidden variation in compound response. [PDF]
, 2020 Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and
Bae, Song Yi +5 more
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Cell Death in the Kidney [PDF]
International Journal of Molecular Sciences, 2019 Apoptotic cell death is usually a response to the cell’s microenvironment. In the kidney, apoptosis contributes to parenchymal cell loss in the course of acute and chronic renal injury, but does not trigger an inflammatory response. What distinguishes necrosis from apoptosis is the rupture of the plasma membrane, so necrotic cell death is accompanied ...
Priante G. +4 more
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Role of Oxidative Stress in Liver Disorders
Livers, 2022 Oxygen is vital for life as it is required for many different enzymatic reactions involved in intermediate metabolism and xenobiotic biotransformation.
Laura Conde de la Rosa +4 more
doaj +1 more source
Cell Death and Disease, 2020 Radiotherapy is commonly used as a cytotoxic treatment of a wide variety of tumors. Interestingly, few case reports underlined its potential to induce immune-mediated abscopal effects, resulting in regression of metastases, distant from the irradiated ...
Sandy Adjemian +13 more
doaj +1 more source
Neuron, 1998 We thank J.-F. Brunet, P. G. H. Clarke, O. deLapeyriere, P. Golstein, J.-C. Martinou, C. Mulle, and R. W. Oppenheim for thoughtful comments on the manuscript and C. Waldmann for artwork. In a short review such as this, it is not possible to establish precedence for all ideas or mechanisms, many of which originate from (or are still confined to) studies
Brigitte Pettmann +1 more
openaire +2 more sources
Alternative cell death pathways and cell metabolism [PDF]
, 2013 While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
core +2 more sources
Bio-Protocol, 2013 The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela +2 more
doaj +1 more source
Current Biology, 1996 Apoptosis, or programmed cell death, is the physiological process whereby individual cells are deliberately eliminated to achieve homeostasis and proper metazoan development. Numerous genes have recently been identified that are involved in apoptosis: some are believed to encode death effectors, whereas others encode positive or negative regulators of ...
Arul M. Chinnaiyan, Vishva M. Dixit
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The convergence of radiation and immunogenic cell death signaling pathways. [PDF]
, 2012 Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of highly regulated processes. Radiation-induced tumor cell death has been studied extensively in vitro and is widely attributed to multiple distinct mechanisms ...
Barcellos-Hoff, Mary H +4 more
core +2 more sources