Results 11 to 20 of about 3,312,655 (209)
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GIAMPIETRI, Claudia +2 more
openaire +6 more sources
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD risk than men,
Carlos Cuño-Gómiz +7 more
doaj +1 more source
Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore
The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned ‘twenty-five’. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being reported.
Anees Rahman Cheratta +5 more
doaj +1 more source
In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease.
Marie-Anaïs Locquet +6 more
doaj +1 more source
Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment.
Blanca Cucarull +7 more
doaj +1 more source
Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells.
Dmitri V. Krysko +5 more
doaj +1 more source
We thank J.-F. Brunet, P. G. H. Clarke, O. deLapeyriere, P. Golstein, J.-C. Martinou, C. Mulle, and R. W. Oppenheim for thoughtful comments on the manuscript and C. Waldmann for artwork. In a short review such as this, it is not possible to establish precedence for all ideas or mechanisms, many of which originate from (or are still confined to) studies
Pettmann, Brigitte +1 more
openaire +2 more sources
Background Rodents, such as mice, are vulnerable targets, and potential intermediate hosts, of SARS-CoV-2 variants of concern, including Alpha, Beta, Gamma, and Omicron.
Yichao Zhu +9 more
doaj +1 more source
Measurement and models accounting for cell death capture hidden variation in compound response. [PDF]
Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and
Bae, Song Yi +5 more
core +1 more source
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation [PDF]
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases.
Bertrand, Mathieu +11 more
core +1 more source

