Results 21 to 30 of about 3,307,555 (359)
Entosis: The emerging face of non-cell-autonomous type IV programmed death
Biomedical Journal, 2017 The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological ...
Isabelle Martins +10 more
doaj +1 more source
Cell-in-cell structure mediates in-cell killing suppressed by CD44
Cell Discovery, 2022 Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells.
Yan Su +17 more
doaj +1 more source
International Journal of Cell Biology, 2010 This special issue on Cell Stress and Cell Death is aimed at bringing together recent developments in the fields of cellular stress and cell death and, in particular, the interplay between cell stress responses and cell death. The special issue opens with a review by S. Fulda et al.
Afshin Samali +4 more
openaire +6 more sources
Cell Death and Disease, 2021 Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil +6 more
doaj +1 more source
Frontiers in Endocrinology, 2022 BackgroundDiabetes mellitus (DM) is a global health problem, and it has become a shocking threat in the contemporary era. The objective of this study was to analyze the safety of sotagliflozin in patients with DM systematically and intuitively.MethodsOn ...
Feifei Zhou +7 more
doaj +1 more source
How to target apoptosis signaling pathways for the treatment of pediatric cancers [PDF]
, 2013 Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors.
Fulda, Simone
core +2 more sources
Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics
OncoImmunology, 2017 The expression “immunogenic cell death” (ICD) refers to a functionally unique form of cell death that facilitates (instead of suppressing) a T cell-dependent immune response specific for dead cell-derived antigens. ICD critically relies on the activation
Abhishek D. Garg +8 more
doaj +1 more source
Macrophage biology plays a central role during ionizing radiation-elicited tumor response
Biomedical Journal, 2017 Radiation therapy is one of the major therapeutic modalities for most solid tumors. The anti-tumor effect of radiation therapy consists of the direct tumor cell killing, as well as the modulation of tumor microenvironment and the activation of immune ...
Qiuji Wu +5 more
doaj +1 more source
Cells, 2022 The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer +4 more
doaj +1 more source
Cell Death in Development [PDF]
Cell, 1999 D. L. V. is supported by grants to the Walter and Eliza Hall Institute from the National Health and Research Council (RegKey 973002) and the Anti-Cancer Council of Victoria.
David L. Vaux, Stanley J. Korsmeyer
openaire +3 more sources