Results 41 to 50 of about 3,307,555 (359)

Endoplasmic reticulum involvement in yeast cell death [PDF]

open access: yes, 2012
Yeast cells undergo programed cell death (PCD) with characteristic markers associated with apoptosis in mammalian cells including chromatin breakage, nuclear fragmentation, reactive oxygen species generation, and metacaspase activation.
Austriaco, Nicanor
core   +3 more sources

Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]

open access: yes, 2019
Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin   +10 more
core   +2 more sources

Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]

open access: yes, 2017
International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu   +10 more
core   +3 more sources

Editorial: Yeast cell aging and death [PDF]

open access: yes, 2018
A conspicuous amount of knowledge about the molecular biol- ogy of the cell has come from studies on yeast Saccharomyces cere- visiae, mostly because of its unrivaled qualities as a toolkit for molecular genetics study.
Cristina Mazzoni, Sergio Giannattasio
core   +1 more source

SIRT1 inhibits mitochondrial hyperfusion associated mito-bulb formation to sensitize oral cancer cells for apoptosis in a mtROS-dependent signalling pathway

open access: yesCell Death and Disease, 2023
SIRT1 (NAD-dependent protein deacetylase sirtuin-1), a class III histone deacetylase acting as a tumor suppressor gene, is downregulated in oral cancer cells.
Srimanta Patra   +8 more
doaj   +1 more source

Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells

open access: yesCells, 2022
Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...
Ditte L. Fogde   +9 more
doaj   +1 more source

Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease [PDF]

open access: yes, 2003
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Czech, Christian   +11 more
core   +1 more source

Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

open access: yesNature Communications, 2020
Lysosomes are intracellular organelles containing degradative enzymes, and leakage of lysosomal contents into the cell is thought to trigger cell death.
Saara Hämälistö   +11 more
doaj   +1 more source

Crucial cross-talk of interleukin-1β and progesterone in human choriocarcinoma [PDF]

open access: yes, 2012
Copyright @ 2012 Spandidos Publications Ltd. This article can be accessed from the links below.This article has been made available through the Brunel Open Access Publishing Fund.Choriocarcinoma is a highly malignant epithelial tumour that is most often ...
Karteris, E   +4 more
core   +1 more source

The Shape of Cell Death [PDF]

open access: yesBiochemical and Biophysical Research Communications, 1997
Cell death, a scheduled event during development and tissue turnover, or the ultimate consequence of toxic or pathologic insults seems to involve a relatively limited number of execution pathways. This reflects the evolution of an organized sequence of events perhaps converging onto final common pathways that are used to dispose of unwanted or injured ...
Leist, Marcel, Nicotera, Pierluigi
openaire   +3 more sources

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