Results 61 to 70 of about 2,113,177 (314)
Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background
Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun +33 morewiley +1 more sourceEffectiveness of a Novel Low‐Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb‐Threatening Ischemia: A Single‐Center Retrospective Study
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background
Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...Kunihiro Ishioka, Takayasu Ohtake, Kei Ohmori, Chika Shibuya, Tomoki Tsukahara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Yusuke Tsukamoto, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi +12 morewiley +1 more sourceMonocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]
, 2012 Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.Mitchell, T.J., Timothy J. Mitchell (150478), Moira K. B. Whyte (150482), David H. Dockrell (114218), Read Robert C., Daigneault, Marc, Daigneault Marc, De Silva, T.I., Helen M. Marriott (150472), De Silva Thushan I., Marriott, Helen M, Preston, Julie A, Dockrell, David H, Marriott, H.M., Julie A Preston, Thushan I. De Silva, De Silva, Thushan I., Dockrell, David H., Whyte, M.K.B., Martin A. Bewley, Preston, Julie A., Mitchell Timothy J., Andrea M. Mitchell, Timothy J Mitchell, Whyte, Moira K B, Mitchell Andrea M., Thushan I. De Silva (150466), Moira K. B. Whyte, Preston Julie A., Helen M Marriott, Preston, J.A., Martin A. Bewley (150467), Robert C Read, Bewley, M.A., Marc Daigneault (150463), Marc Daigneault, Dockrell, D.H., Mitchell, Andrea M; id_orcid, Whyte Moira K. B., Whyte, Moira K. B., Marriott Helen M., Mitchell, Andrea M., Read, Robert C., Robert C. Read (145234), De Silva, Thushan I, Mitchell, Timothy J., Read, R.C., David H. Dockrell, Julie A. Preston (150469), Andrea M. Mitchell (150475), Mitchell, Timothy J, David H Dockrell, Moira K B Whyte, Marriott, Helen M., Mitchell, A.M., Timothy J. Mitchell, Andrea M Mitchell, Bewley, Martin A, Daigneault, M., Read, Robert C, Robert C. Read, Dockrell David H., Bewley, Martin A., Martin A Bewley, Helen M. Marriott, Julie A. Preston, Dockrell, David, Bewley Martin A., Thushan I De Silva +68 morecore +1 more sourceDegradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis
Cell Reports, 2017 Summary: We describe a mechanism by which the anti-apoptotic B cell lymphoma 2 (Bcl-2) protein is downregulated to induce apoptosis. ARTS (Sept4_i2) is a tumor suppressor protein that promotes cell death through specifically antagonizing XIAP (X-linked ...Natalia Edison, Yael Curtz, Nicole Paland, Dana Mamriev, Nicolas Chorubczyk, Tali Haviv-Reingewertz, Nir Kfir, David Morgenstern, Meital Kupervaser, Juliana Kagan, Hyoung Tae Kim, Sarit Larisch +11 moredoaj +1 more sourceEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceCD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE. [PDF]
, 2012 BACKGROUND: Most adults infected with HIV achieve viral suppression within a year of starting combination antiretroviral therapy (cART). It is important to understand the risk of AIDS events or death for patients with a suppressed viral load.S. Matheron, M. Sharland, Niels Obel (135891), R. Thiebaut, Jesper Grarup (453101), José M Miro, Reiss, Peter, Furrer, H, D. Haerry, A. Cozzi Lepri, Josefa Muñoz (11702276), Miró Meda, José M. (José María), 1956-, Hansjakob Furrer (93994), Ole Kirk (314889), Gazzard, B, G. Touloumi, Raffi, F, Josefa Muñoz, J. Reekie, A. Castagna, G. Fatkenheuer, R. Lodwick, Niels Obel, Sophie Grabar (697347), S. Grabar, T. Goetghebuer, J. Grarup, The Opportunistic Infections Project Team of the Collaboration o (16174457), D. Gibb, A. Antinori, Peter Reiss (4933), E. Girardi, José M Miro (16174463), Raffi, Francois, Antonella Castagna (255402), Grarup, Jesper, F. Engsig, Peter Reiss, Kirk, Ole, F. Gutierrez, Opportunistic Infections Project Team of the Collaboration of Ob,, H. Furrer, J. Casabona, M. Egger, O. Lambotte, Sylvie Ayayi (16174460), J. Ghosn, V. Bouteloup, Obel, N, Young, Jim, De Wit, Stéphane, Chêne, Geneviève, Heiner Bucher, M. Psichogiou, Mina Psichogiou (146065), Y. Young, C. Stephan, Chêne, G, Martin Fisher (300134), C. Lewden, A. D’Arminio Monforte, Ayayi, Sylvie, R. Zangerle, Young, J, S. De Wit, Laurence Meyer (130347), Bucher, Heiner, Antonella Castagna, Miró, José María, Geneviève Chêne, C. Sabin, Meyer, Laurence, Félix Gutierrez, Miro, José M, P. Morlat, P. Tookey, C. Torti, Gazzard, Brian, R. Paredes, Miro, José M., The Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord (614233), J. M. Miro, V. Le Moing, I. Weller, Francois Raffi, A. Mocroft, C. Smit, Jim Young (252690), S. Ayayi, Grarup, J, Jesper Kjaer, Sharland, M, Brian Gazzard, M. Prins, J. Warszawski, A. Noguera Julian, M. Garrido, De Wit, S, F. de Wolf, H. Bucher, Muñoz, J, J. Miro, C. Thorne, O. Kirk, Francois Raffi (6269708), Stéphane De Wit, Jesper Grarup, Gutierrez, Félix, J. Kjaer, Kjaer, J, J. Munoz, Bucher, Heiner H.C., Ole Kirk, V. von Wyl, C. Leport, A. Scherrer, L. Galli, Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord, Kjaer, Jesper, D. Costagliola, J. Sterne, Sophie Grabar, Opportunistic Infections Project Team of the Collaboration of Ob, P. Reiss, F. Dabis, Heiner Bucher (3510056), Meyer, L, A. Antoniadou, Furrer, Hansjakob, Jim Young, J. Ramos, J. Bohlius, A. Phillips, Hansjakob Furrer, Noguera Julian, Antoni, Sylvie Ayayi, Collaboration of Observational HIV Epidemiological Research Europe (COHERE), Castagna, A, Geneviève Chêne (252698), Ayayi, S, Obel, Niels, C. Colin, Bucher, H, F. Raffi, R. Teira, Jesper Kjaer (453100), Castagna, Antonella, Psichogiou, M, L. Meyer, N. Brockmeyer, A. Rauch, G. Chene, Miro, JM, Grabar, Sophie, M. Puoti, Kirk, O, Laurence Meyer, Reekie, Joanne ; https://orcid.org/, Muñoz, Josefa, B. Gazzard, N. Obel, M. M. Krause, J. Del Amo, Mina Psichogiou, L. Wittkop, M. Battegay, Grabar, S, Stéphane De Wit (262489), Brian Gazzard (4921), M. Fisher, Reiss, P, Gutierrez, F, S. Perez Hoyos, M. Dorrucci, Mike Sharland (258810), M. Paulsen, B. Ledergerber, Mike Sharland, Sharland, Mike, Psichogiou, Mina, C. Mussini, Félix Gutierrez (379459) +181 morecore +1 more sourceDrug toxicity assessment: cell proliferation versus cell death
, 2022 Analysis of the toxicity of chemotherapeutic drugs is one of the main tasks of clinical pharmacology. Decreased viability of tumor cells may reflect two important physiological processes, namely the arrest of proliferation associated with disturbances in Sazonova, Elena V., Chesnokov, Mikhail S., Zhivotovsky, Boris, Kopeina, Gelina S., Chesnokov, MS, Sazonova, EV, Zhivotovsky, B,, Kopeina, GS +7 morecore +1 more sourceTumor endothelial cell autophagy is a key vascular‐immune checkpoint in melanoma
EMBO Molecular Medicine, 2023 Tumor endothelial cells (TECs) actively repress inflammatory responses and maintain an immune‐excluded tumor phenotype. However, the molecular mechanisms that sustain TEC‐mediated immunosuppression remain largely elusive.Jelle Verhoeven, Kathryn A Jacobs, Francesca Rizzollo, Francesca Lodi, Yichao Hua, Joanna Poźniak, Adhithya Narayanan Srinivasan, Diede Houbaert, Gautam Shankar, Sanket More, Marco B Schaaf, Nikolina Dubroja Lakic, Maarten Ganne, Jochen Lamote, Johan Van Weyenbergh, Louis Boon, Oliver Bechter, Francesca Bosisio, Yasuo Uchiyama, Mathieu JM Bertrand, Jean Christophe Marine, Diether Lambrechts, Gabriele Bergers, Madhur Agrawal, Patrizia Agostinis +24 moredoaj +1 more source
