Results 1 to 10 of about 13,702,363 (424)
Helper T cell differentiation [PDF]
Cellular & Molecular Immunology, 2019 CD4
Jordy Saravia +2 more
openaire +3 more sources
Ratio control in a cascade model of cell differentiation [PDF]
, 2009 We propose a kind of reaction-diffusion equations for cell differentiation, which exhibits the Turing instability. If the diffusivity of some variables is set to be infinity, we get coupled competitive reaction-diffusion equations with a global feedback term. The size ratio of each cell type is controlled by a system parameter in the model. Finally, we
A. V. Hill +6 more
arxiv +3 more sources
Criticality in Cell Differentiation [PDF]
arXiv, 2016 Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components. Several theoretical studies suggest that cell differentiation is a bifurcation phenomenon,
Bose, Indrani, Pal, Mainak
arxiv +7 more sources
Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis [PDF]
arXiv, 2000 Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''. Two fundamental features of stem cell systems - stochastic differentiation of stem cells and the robustness of a system due to regulation of this ...
Furusawa, Chikara, Kaneko, Kunihiko
arxiv +5 more sources
THE DIFFERENTIATION OF CELLS [PDF]
Proceedings of the National Academy of Sciences, 1964 T. M. Sonneborn
openaire +3 more sources
Charting cellular identity during human in vitro β-cell differentiation
Nature, 2019 Adrian Veres +2 more
exaly +2 more sources
Canadian Respiratory Journal, 2022 Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading
Lan Wang +7 more
doaj +1 more source
Overview of CircRNAs Roles and Mechanisms in Liver Fibrosis
Biomolecules, 2023 Liver fibrosis represents the reversible pathological process with the feature of the over-accumulation of extracellular matrix (ECM) proteins within the liver, which results in the deposition of fibrotic tissues and liver dysfunction. Circular noncoding
Gaiping Wang +6 more
doaj +1 more source
Cell cycle: To differentiate or not to differentiate? [PDF]
Current Biology, 2000 Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Robert J. Duronio, Denise L. Myster
openaire +2 more sources
Mitochondrial Dysfunction and Chronic Liver Disease
Current Issues in Molecular Biology, 2022 Mitochondria are generally considered the powerhouse of the cell, a small subcellular organelle that produces most of the cellular energy in the form of adenosine triphosphate (ATP). In addition, mitochondria are involved in various biological functions,
Chunyan Zhang +5 more
doaj +1 more source