Results 1 to 10 of about 1,464,786 (217)

THE DIFFERENTIATION OF CELLS [PDF]

open access: greenProceedings of the National Academy of Sciences, 1964
T. M. Sonneborn
openalex   +3 more sources

Cell cycle: To differentiate or not to differentiate? [PDF]

open access: yesCurrent Biology, 2000
Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Robert J. Duronio, Denise L. Myster
openaire   +2 more sources

Criticality in Cell Differentiation [PDF]

open access: yesJournal of Biosciences, 2016
AbstractCell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components.
Bose, Indrani, Pal, Mainak
openaire   +5 more sources

Dendritic Cell Differentiation [PDF]

open access: yesThe Journal of Immunology, 2004
Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A   +4 more
openaire   +5 more sources

Ghrelin and cell differentiation [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2008
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a gastric hormone that has been found to have a wide variety of biological functions. This review summarizes our current understanding of the effects of ghrelin on cell differentiation and tissue development, with an emphasis on the lineage determination of mesenchymal stem ...
Wenjiao An   +4 more
openaire   +4 more sources

Cell cycle and differentiation [PDF]

open access: yesCurrent Opinion in Plant Biology, 2004
The development of multicellular organisms relies on the temporal and spatial control of cell proliferation and cell growth. The relationship between cell-cycle progression and development is complex and characterized by mutual dependencies. On the level of the individual cell, this interrelationship has implications for pattern formation and cell ...
Jakoby, M., Schnittger, A.
openaire   +3 more sources

Helper T cell differentiation [PDF]

open access: yesCellular & Molecular Immunology, 2019
CD4+ T helper cells are key regulators of host health and disease. In the original model, specialized subsets of T helper cells are generated following activation through lineage-specifying cytokines and transcriptional programs, but recent studies have revealed increasing complexities for CD4+ T-cell differentiation. Here, we first discuss CD4+ T-cell
Jordy Saravia   +2 more
openaire   +2 more sources

Cell Differentiation and Checkpoint [PDF]

open access: yesInternational Journal of Cancer Research and Molecular Mechanisms ( ISSN 2381-3318 ), 2015
DNA damage is induced in many types of cells by internal and external cell stress. When DNA is damaged, DNA Damage Response (DDR) programs are activated to repair the DNA lesions in order to preserve genomic integrity and suppress subsequent malignant transformation.
Sara Cuesta Sancho, Toru Ouchi
openaire   +3 more sources

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