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THE DIFFERENTIATION OF CELLS [PDF]
T. M. Sonneborn
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Cell cycle: To differentiate or not to differentiate? [PDF]
Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Robert J. Duronio, Denise L. Myster
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Criticality in Cell Differentiation [PDF]
AbstractCell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components.
Bose, Indrani, Pal, Mainak
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Dendritic Cell Differentiation [PDF]
Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A+4 more
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Ghrelin and cell differentiation [PDF]
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a gastric hormone that has been found to have a wide variety of biological functions. This review summarizes our current understanding of the effects of ghrelin on cell differentiation and tissue development, with an emphasis on the lineage determination of mesenchymal stem ...
Wenjiao An+4 more
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Cell cycle and differentiation [PDF]
The development of multicellular organisms relies on the temporal and spatial control of cell proliferation and cell growth. The relationship between cell-cycle progression and development is complex and characterized by mutual dependencies. On the level of the individual cell, this interrelationship has implications for pattern formation and cell ...
Jakoby, M., Schnittger, A.
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Helper T cell differentiation [PDF]
CD4+ T helper cells are key regulators of host health and disease. In the original model, specialized subsets of T helper cells are generated following activation through lineage-specifying cytokines and transcriptional programs, but recent studies have revealed increasing complexities for CD4+ T-cell differentiation. Here, we first discuss CD4+ T-cell
Jordy Saravia+2 more
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Cell Differentiation and Checkpoint [PDF]
DNA damage is induced in many types of cells by internal and external cell stress. When DNA is damaged, DNA Damage Response (DDR) programs are activated to repair the DNA lesions in order to preserve genomic integrity and suppress subsequent malignant transformation.
Sara Cuesta Sancho, Toru Ouchi
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ON A COMBINATION OF SUBSTANCES WHICH EXCITES AMÅ’BOID MOVEMENT IN LEUCOCYTES, BY WHICH LIVING CAN BE DIFFERENTIATED FROM DEAD CELLS. [PDF]
H.C. Ross
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Germ Cell Movements and Sex Differentiation of the Gonads in the Drosophila Embryo [PDF]
B. P. Sonnenblick
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