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Cell cycle: To differentiate or not to differentiate? [PDF]
Current Biology, 2000 Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Robert J. Duronio, Denise L. Myster
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Criticality in Cell Differentiation [PDF]
Journal of Biosciences, 2016 AbstractCell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components.
Bose, Indrani, Pal, Mainak
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The identification of markers of macrophage differentiation in PMA-stimulated THP-1 Cells and monocyte-derived macrophages [PDF]
, 2010 Differentiated macrophages are the resident tissue phagocytes and sentinel cells of the innate immune response. The phenotype of mature tissue macrophages represents the composite of environmental and differentiation-dependent imprinting.
David H. Dockrell +5 more
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A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells. [PDF]
, 2019 Pancreatic endocrine cell differentiation is orchestrated by the action of transcription factors that operate in a gene regulatory network to activate endocrine lineage genes and repress lineage-inappropriate genes.
Carrano, Andrea C +15 more
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Evidence for an interplay between cell cycle progression and the initiation of differentiation between life cycle forms of African trypanosomes [PDF]
, 1994 Successful transmission of the African trypanosome between the mammalian host blood-stream and the tsetse fly vector involves dramatic alterations in the parasite's morphology and biochemistry.
Gull, K, Matthews, K R
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Dendritic Cell Differentiation [PDF]
The Journal of Immunology, 2004 Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A +4 more
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Interleukin-33 promoting Th1 lymphocyte differentiation dependents on IL-12 [PDF]
, 2016 No abstract available.The pro-Th2 cytokine IL-33 is now emerging as an important Th1 cytokine-IFN-γ inducer in murine CD4+ T cells that is essential for protective cell-mediated immunity against viral infection in mice. However, whether IL-33 can promote
Komai-Koma, Mousa +5 more
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Ghrelin and cell differentiation [PDF]
Acta Biochimica et Biophysica Sinica, 2008 Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a gastric hormone that has been found to have a wide variety of biological functions. This review summarizes our current understanding of the effects of ghrelin on cell differentiation and tissue development, with an emphasis on the lineage determination of mesenchymal stem ...
Wenjiao An +4 more
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Cell cycle and differentiation [PDF]
Current Opinion in Plant Biology, 2004 The development of multicellular organisms relies on the temporal and spatial control of cell proliferation and cell growth. The relationship between cell-cycle progression and development is complex and characterized by mutual dependencies. On the level of the individual cell, this interrelationship has implications for pattern formation and cell ...
Jakoby, M., Schnittger, A.
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Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells [PDF]
, 2012 It has previously been demonstrated that cell shape can influence commitment of human bone marrow-derived mesenchymal stem cells (hBMCs) to adipogenic, osteogenic, chondrogenic, and other lineages.
Chen, Christopher S. +2 more
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