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Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling [PDF]
BACKGROUND & AIMS: Drug repositioning offers a shorter approval process than new drug development. We therefore searched large public datasets of drug-induced gene expression signatures to identify agents that might be effective against hepatocellular carcinoma (HCC).
Chen, Bin +7 more
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The rapidly changing landscape in mature T‐cell lymphoma (MTCL) biology and management
Ca-A Cancer Journal for Clinicians, 2020Enrica Marchi
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Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
Nature Reviews Molecular Cell Biology, 2016Marcos Malumbres, Piotr Sicinski
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Cubism and the cell cycle: the many faces of the APC/C
Nature Reviews Molecular Cell Biology, 2011Jonathon Pines
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Hit the right spots: cell cycle control by phosphorylated guanosines in alphaproteobacteria
Nature Reviews Microbiology, 2017Regis Hallez, Marie Delaby
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Cell cycle proteins as promising targets in cancer therapy
Nature Reviews Cancer, 2017Tobias Otto, Piotr Sicinski
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Regulation of DNA repair throughout the cell cycle
Nature Reviews Molecular Cell Biology, 2008Dana Branzei, Marco Foiani
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