Results 21 to 30 of about 12,578,619 (347)
Background. The brain is an organ that has an important function potentially exposed to bad influences of radiation, especially on the head neck tumors. Gamma rays interact with body molecules causing damage to DNA and subsequently apoptosis.
Ahmad Bayhaqi Nasir Alam +2 more
doaj +1 more source
A Prospective Randomised Study of Comparison between Conventional and Accelerated Fractionation Radiotherapy in Treatment of Head and Neck Cancers [PDF]
Introduction: Treatment of locally advanced lesions of head and neck cancers include combined modality approach such as surgery, Radiotherapy (RT) and chemotherapy.
M Hemanth +4 more
doaj +1 more source
Summary: Diabetes mellitus is a disease of the hormone-secreting endocrine pancreas. However, increasing evidence suggests that the exocrine pancreas is also involved in the pathogenesis of diabetes.
Laura Steiger +5 more
doaj +1 more source
Optimized protocol for tRNA identification in the ribosomal complexes from human cell lines
Summary: Here, we describe a protocol for tRNA identification in the 60S ribosome-nascent peptide complex co-purified with Nuclear Export Mediator Factor (NEMF), a responsible factor for C-terminal alanine and threonine tailing of the nascent peptide ...
Tsuyoshi Udagawa +2 more
doaj +1 more source
Zinc (Zn) accumulates in breast cancer tumors compared to adjacent healthy tissue. Clinical samples of breast cancer tissue show light Zn isotopic compositions (δ66Zn) relative to healthy tissue. The underlying mechanisms causing such effects are unknown.
Kathrin Schilling +10 more
doaj +1 more source
AN IMPROVED CELL FRACTIONATION PROCEDURE FOR THE PREPARATION OF RAT LIVER MEMBRANE-BOUND RIBOSOMES
A cell fractionation procedure is described which allows the preparation from rat liver of a rough microsome population containing almost 50% of the membrane-bound ribosomes of the tissue.
M. R. Adelman, G. Blobel, D. Sabatini
semanticscholar +1 more source
Cell fractionation of large bowel cancer
The fractionation of cells from human colonic carcinoma, a transplantable colonic carcinoma of the rat, and normal rat colonic mumsa by centrifugation in linear gradients of Ficoll (polysucrose) in tissue culture medium is described. Epithelial cells from human colonic carcinoma showed strong histochemical N-acetyl-@-D-glucosaminidase activity relative
M. Brattain, T. P. Pretlow, T. Pretlow
semanticscholar +3 more sources
Subcellular Fractionation of Cultured Human Cell Lines
Subcellular localization is crucial for the proper functioning of a protein. Deregulation of subcellular localization may lead to pathological consequences and result in diseases like cancer.
Zhuoyou Yu, Zhiguang Huang, Maria Lung
doaj +1 more source
Protocol to determine the subcellular localization of protein interactions in murine keratinocytes
Summary: Protein activities and interactions are determined by their subcellular localization. Elucidating the network of protein-protein interactions at a spatial resolution is essential for understanding the complexity of protein functions, their ...
Lisa Müller
doaj +1 more source
A double-label protocol was used to estimate the extent of leakage and relocation artifacts that affect exocrine pancreatic proteins in cell fractionation experiments.
G. Scheele, G. Palade, A. Tartakoff
semanticscholar +1 more source

