Results 1 to 10 of about 20,216,403 (408)

Skeletal muscle hypertrophy: cell growth is cell growth.

open access: yesAm J Physiol Cell Physiol
Roberts et al. have provided an insightful counterpoint to our review article on the utility of the synergist ablation model. The purpose of this review is to provide some further dialogue regarding the strengths and weaknesses of the synergist ablation ...
Burke BI   +4 more
europepmc   +2 more sources

Nucleotide imbalance decouples cell growth from cell proliferation

open access: yesNature Cell Biology, 2021
Nucleotide metabolism supports RNA synthesis and DNA replication to enable cell growth and division. Nucleotide depletion can inhibit cell growth and proliferation, but how cells sense and respond to changes in the relative levels of individual ...
Frances F. Diehl   +8 more
semanticscholar   +1 more source

HS3ST2 expression induces the cell autonomous aggregation of tau

open access: yesScientific Reports, 2022
Heparan sulfates have long been known to intracellularly accumulate in Alzheimer’s disease neurons, where they colocalize with neurofibrillary tangles made of abnormally phosphorylated and aggregated tau protein.
M. B. Huynh   +6 more
doaj   +1 more source

Retinoic acid regulates erythropoietin production cooperatively with hypoxia-inducible factors in human iPSC-derived erythropoietin-producing cells

open access: yesScientific Reports, 2021
Erythropoietin (EPO) is a crucial hormone for erythropoiesis and produced by adult kidneys. Insufficient EPO production in chronic kidney disease (CKD) can cause renal anemia.
Naoko Katagiri   +7 more
doaj   +1 more source

A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

open access: yesNature Communications, 2021
T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi   +19 more
doaj   +1 more source

Principles of cell growth

open access: yes, 2023
This is a chapter from the free textbook "Economic Principles in Cell Biology" In this chapter, we discuss the principles underpinning models of microbial growth, articulating the foundational assumptions that govern these systems. These premises serve as tools to unravel a sequence of progressively intricate examples, each with a unique layer of ...
Golan, Ohad   +5 more
openaire   +2 more sources

Mechanics of cell growth [PDF]

open access: yesMechanics Research Communications, 2012
Cell growth describes an essential feature of biological tissues. This growth process may be modeled by using a set of relatively simple governing equations based on the axioms of mass and momentum balance, and using a continuum framework that describes cells and tissues as mixtures of a solid matrix, a solvent and multiple solutes.
Clark T. Hung   +3 more
openaire   +3 more sources

Enhanced mechanical heterogeneity of cell collectives due to temporal fluctuations in cell elasticity [PDF]

open access: yesPhys. Rev. E 107, 014401 (2023), 2022
Cells are dynamic systems characterized by temporal variations in biophysical properties such as stiffness and contractility. Recent studies show that the recruitment and release of actin filaments into and out of the cell cortex - a network of proteins underneath the cell membrane - leads to cell stiffening prior to division and softening immediately ...
arxiv   +1 more source

Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

open access: yesScience, 2020
A cell size sensor Efforts continue to uncover the long-sought mechanism by which cells coordinate growth and cell division to maintain a constant size. Zatulovskiy et al.
E. Zatulovskiy   +4 more
semanticscholar   +1 more source

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