Results 111 to 120 of about 20,216,403 (408)

Morphology of Proliferating Epithelial Cellular Tissue [PDF]

, 2018
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simulation model for mechanical cell division. The model reproduces structures of simple multi-cellular organisms via simple rules for selective division and ...
Baumeier, Björn, Karttunen, Mikko, Madhikar, Pranav, Åström, Jan   +3 more
core   +2 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth

Journal of Experimental Medicine, 1999
Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses, including cell growth, differentiation, and even death. Here we describe a novel member of the TNF family, designated BAFF (for B cell activating factor belonging ...
P. Schneider, F. Mackay, Véronique Steiner, K. Hofmann, J. Bodmer, N. Holler, C. Ambrose, P. Lawton, S. Bixler, H. Acha-Orbea, D. Valmori, P. Romero, C. Werner‐Favre, R. Zubler, J. Browning, J. Tschopp   +15 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism

Communications Biology
Memory T cells demonstrate superior in vivo persistence and antitumor efficacy. However, methods for manufacturing less differentiated T cells are not yet well-established.
Shin-ichiro Takayanagi, Sayaka Chuganji, Masahiro Tanaka, Bo Wang, Saki Hasegawa, Ken Fukumoto, Nariaki Wasano, Makoto Kakitani, Nakaba Ochiai, Yohei Kawai, Tatsuki Ueda, Akihiro Ishikawa, Yuko Kurimoto, Asami Fukui, Sanae Kamibayashi, Eri Imai, Atsushi Kunisato, Hajime Nozawa, Shin Kaneko   +18 more
doaj   +1 more source

The cell-cell channel in the control of growth

Seminars in Cell Biology, 1992
Several lines of evidence indicate that the cell-cell channels in gap junction are conduits for growth-regulating signals. Experimental upregulation of the channels by retinoids causes inhibition of cellular growth and, conversely, their downregulation by oncogenes, e.g. activated src, stimulates growth.
Birgit Rose, Werner R. Loewenstein
openaire   +2 more sources

Deterministic and stochastic descriptions of gene expression dynamics

, 2012
A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or implicitly etc ...
A.M. Walczak, C. Tan, C.V. Rao, D.L. Cook, David Gomez, E. Andrianantoandro, E.M. Ozbudak, H. Bremer, H.H. McAdams, I. Golding, J. Hasty, J. Hasty, J. Paulsson, J. Paulsson, J. Peccoud, J. Yu, J.A. Bernstein, J.L. Spudich, K. Nath, L. Bintu, L. Cai, M. Kaern, M. Scott, M. Scott, M. Thattai, M.B. Elowitz, M.E. Csete, M.E. Wall, M.S. Ko, N. Brenner, N. Mitarai, N.A. Cookson, N.J. Guido, O.G. Berg, O.G. Berg, P. Guptasarma, P. Wang, P.S. Swain, R. Kwok, Rahul Marathe, S. Cooper, S. Cooper, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Reeh, Stefan Klumpp, U. Alon, Veronika Bierbaum, Y. Taniguchi   +51 more
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Growth of Streptococcus bovis and a Butyrivibrio in batch and continuous culture and the relationship of molar growth yield to intermicrobial competition : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology. [PDF]

, 1974
Cell growth yield of Streptococcus bovis and Butyrivibrio were determined in batch cultures where growth was separately limited by glucose, CO2 and trypticase.
Asmundson, Roderick Vincent
core  

Oligodendroglioma cells lack glutamine synthetase and are auxotrophic for glutamine, but do not depend on glutamine anaplerosis for growth [PDF]

, 2018
In cells derived from several types of cancer, a transcriptional program drives high consumption of glutamine (Gln), which is used for anaplerosis, leading to a metabolic addiction for the amino acid. Low or absent expression of Glutamine Synthetase (GS),
Andreoli, Roberta, Bianchi, Massimiliano G., Bussolati, Ovidio, Chiu, Martina, Ciociola, Tecla, Lagrasta, Costanza A M, Ottaviani, Laura, Tardito, Saverio, Taurino, Giuseppe   +8 more
core   +2 more sources