Results 11 to 20 of about 5,474,086 (199)
A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth
Nature Communications, 2016 Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain ...
Joseph H.A. Vissers +3 more
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Orphanet Journal of Rare Diseases, 2020 Background Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disease characterized by heterotopic ossification (HO) in soft tissues and caused by a mutation of the ACVR1A/ALK2 gene.
Hirotsugu Maekawa +7 more
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Influence of cell cycle phase on calcification in the coccolithophore Emiliania huxleyi [PDF]
, 2008 Calcification of the cosmopolitan coccolithophore species Emiliania huxleyi was investigated in relation to the cell division cycle with the use of batch cultures.
Antia, Avan +2 more
core +1 more source
Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue
Nature Communications, 2017 Torsade de Pointes (TdP) is a life-threatening ventricular arrhythmia often caused by drugs. In response to an urgent need for human tissue TdP models, here the authors describe a 3D human iPS cell-engineered heart tissue that generates TdP in response ...
Masahide Kawatou +6 more
doaj +1 more source
eLife, 2016 Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear.
Kenji Kamimoto +5 more
doaj +1 more source
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer [PDF]
, 2007 Colorectal cancer is initiated in colonic crypts. A succession of genetic mutations or epigenetic changes can lead to homeostasis in the crypt being overcome, and subsequent unbounded growth.
M. D. Johnston +24 more
core +4 more sources
Mechanics of cell growth [PDF]
Mechanics Research Communications, 2012 Cell growth describes an essential feature of biological tissues. This growth process may be modeled by using a set of relatively simple governing equations based on the axioms of mass and momentum balance, and using a continuum framework that describes cells and tissues as mixtures of a solid matrix, a solvent and multiple solutes.
Gerard A, Ateshian +3 more
openaire +2 more sources
Stem Cell Reports, 2015 To develop a culture system for large-scale production of mature hepatocytes, liver progenitor cells (LPCs) with a high proliferation potential would be advantageous.
Taketomo Kido +7 more
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Podoplanin as an Attractive Target of CAR T Cell Therapy
Cells, 2020 To date, various kinds of cancer immunotherapy methods have been developed, but T cell immunotherapy is one of the most promising strategies. In general, T cell receptor (TCR) or chimeric antigen receptor (CAR) is used to modify the antigen specificity ...
Masazumi Waseda, Shin Kaneko
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Mesenchymal Cell Growth Factors [PDF]
Critical Reviews in Oral Biology & Medicine, 1990 The study of growth factors has involved diverse fields that share a common interest in factors regulating cellular proliferation. These disciplines include wound healing since growth factors initiate repair or regeneration of injured tissue; cancer because transformed cells have been shown to have deregulated expression of growth factor genes; and ...
D T, Graves, D L, Cochran
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