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Mesenchymal Cell Growth Factors [PDF]
The study of growth factors has involved diverse fields that share a common interest in factors regulating cellular proliferation. These disciplines include wound healing since growth factors initiate repair or regeneration of injured tissue; cancer because transformed cells have been shown to have deregulated expression of growth factor genes; and ...
D T, Graves, D L, Cochran
openaire +2 more sources
Circadian rhythm and cell population growth [PDF]
Molecular circadian clocks, that are found in all nucleated cells of mammals, are known to dictate rhythms of approximately 24 hours (circa diem) to many physiological processes.
Bekkal Brikci +27 more
core +5 more sources
Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention [PDF]
The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation.
A Arlt +91 more
core +6 more sources
Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs
Defects in articular cartilage ultimately result in loss of joint function. Repairing cartilage defects requires cell sources. We developed an approach to generate scaffoldless hyaline cartilage from human induced pluripotent stem cells (hiPSCs).
Akihiro Yamashita +7 more
doaj +1 more source
Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle. [PDF]
In this issue of Cancer Cell, Hydbring and colleagues define a novel class of microRNAs (miRNAs), deemed cell-cycle-targeting miRNAs, that target several cyclins/CDKs, reduce tumor cell growth, and induce apoptosis.
Knudsen, Karen E., Schiewer, Matthew J.
core +2 more sources
KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway. [PDF]
Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells ...
Chen, Miao +18 more
core +1 more source
Because of their close biological similarity to humans, non-human primate (NHP) models are very useful for the development of induced pluripotent stem cell (iPSC)-based cell and regenerative organ transplantation therapies.
Yoshihiro Iwamoto +11 more
doaj +1 more source
In the fibers of many plant species after the formation of secondary cell walls, cellulose-enriched cell wall layers (often named G-layers or tertiary cell walls) are deposited which are important in many physiological situations.
Anna Petrova +5 more
doaj +1 more source
Sub-unit cell layer-by-layer growth of Fe3O4, MgO, and Sr2RuO4 thin films
The use of oxide materials in oxide electronics requires their controlled epitaxial growth. Recently, it was shown that Reflection High Energy Electron Diffraction (RHEED) allows to monitor the growth of oxide thin films even at high oxygen pressure ...
Alff, L. +7 more
core +1 more source
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
core +1 more source

