Results 1 to 10 of about 1,067,356 (214)

Novel syngeneic model of anti-mouse CLDN18.2 CAR -T therapy for gastric cancer demonstrates a synergy with TGF-β and PD-L1 inhibitors [PDF]

open access: yesMolecular Therapy: Oncology
There are very few syngeneic mouse cell line models available for gastric cancer owing to the rarity of stomach epithelium-specific promoter. Mouse cell line models are useful to study an immunologically intact tumor microenvironment, especially in the ...
Min-Jung Seo   +12 more
doaj   +2 more sources

Establishment and characterization of HXWMF-1: the first mouse fibroblastic tumor cell line derived from leukemia-associated fibroblasts

open access: yesCancer Cell International, 2021
Background Chemo-resistance is still a major obstacle in leukemia treatment. Accumulating evidence indicates that cancer-associated fibroblasts (CAFs), the most abundant stromal cells in tumor microenvironment (TME), play a crucial role in cancer ...
Yuanyuan Li, Ling Gu
doaj   +1 more source

Role of crocin in several cancer cell lines: An updated review [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality.
Ali Veisi   +5 more
doaj   +1 more source

Establishment and characterization of a canine chondrosarcoma cell line: Mango

open access: yesAnimal Diseases, 2023
In the global progress of bone tumor research, established stable and long-lasting transgenic chondrosarcoma (CSA) cell lines are rare, mainly of murine and human origin, while the establishment of canine CSA cell lines has yet to be reported. This study
Meilin Wang   +10 more
doaj   +1 more source

A Novel Canine Mammary Cancer Cell Line: Preliminary Identification and Utilization for Drug Screening Studies

open access: yesFrontiers in Veterinary Science, 2021
Canine malignant mammary tumor is a dangerously fatal neoplastic disease with poor survival in female dogs. The aim of this study was to preliminary characterize a novel canine mammary cancer cell line, B-CMT, from canine primary mammary gland tumor, and
Rifei Li   +6 more
doaj   +1 more source

A clear cancer cell line (150057) derived from human endometrial carcinoma harbors two novel mutations

open access: yesBMC Cancer, 2020
Background Cell lines are extremely useful for both basic and clinical research. Thus, establishing endometrial cancer cell lines with malignant histology is important. This study aimed to extensively characterize an endometrial clear cell carcinoma cell
Yu-Hsun Chang, Dah-Ching Ding
doaj   +1 more source

Relationship between tumor cell invasiveness and polyploidization. [PDF]

open access: yesPLoS ONE, 2012
A number of studies have shown that tumor cells fuse with other tumor and non-tumor cells. In the present study on tumor cell lines derived from glioblastoma, breast cancer, and melanoma, we estimated the frequency of fusion between tumor cells by ...
Javier Mercapide   +3 more
doaj   +1 more source

The secret lives of cancer cell lines

open access: yesDisease Models & Mechanisms, 2018
The extent of genetic and epigenetic diversity between and within patient tumors is being mapped in ever more detail. It is clear that cancer is an evolutionary process in which tumor cell intrinsic and extrinsic forces shape clonal selection.
Robert E. Hynds   +2 more
doaj   +1 more source

Different toxic effects of YTX in tumor K-562 and lymphoblastoid cell lines

open access: yesFrontiers in Pharmacology, 2015
Yessotoxin (YTX) modulates cellular phosphodiesterases (PDEs). In this regard, opposite effects had been described in the tumor model K-562 cell line and fresh human lymphocytes in terms of cell viability, cyclic adenosine 3´,5´-cyclic monophosphate ...
Andrea Fernández Araújo   +4 more
doaj   +1 more source

Establishment and characterization of a cell line (NOMH-1) originating from a human endometrioid adenocarcinoma of the ovary

open access: yesJournal of Ovarian Research, 2013
Background Cell lines are very useful for clinical and basic research. Thus far, only 11 reports have documented the characteristics of ovarian endometrioid adenocarcinoma cell lines in the literature.
Yamada Takashi   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy