Results 11 to 20 of about 1,067,356 (214)
Global computational alignment of tumor and cell line transcriptional profiles
Nature Communications, 2021 The determination of whether cancer cell lines recapitulate the molecular features of corresponding patient tumours remains essential for the selection of appropriate cell line models for preclinical studies.
Allison Warren +8 more
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5-Azacytidine Enhancing Expression of E-cadherin in Adenocarcinoma Cell Line
Archives of Advances in Biosciences, 2023 Introduction: In this study, we assessed the expression of E-cadherin in HT29 cell line treated with 5-Azacytidine and colorectal cancer patient in an Iranian population. E-cadherin expression promotes metastasis and prognosis of colorectal cancer (CRC).
Sanaz Savabkar +4 more
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Establishment and Characterization of A Human Lung Adenocarcinoma Cell Line, Ch-Huang-1
Chinese Journal of Lung Cancer, 2012 Background and objective Lung cancer is a major worldwide health problem. The aim of this study is to establish a novel Chinese human lung adenocarcinoma cell line and examine its biological characteristics.
Bailing LI +6 more
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Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor. [PDF]
PLoS ONE, 2013 Pheochromocytomas are rare tumors generally arising in the medullary region of the adrenal gland. These tumors release excessive epinephrine and norepinephrine resulting in hypertension and cardiovascular crises for which surgery is the only definitive ...
Hans K Ghayee +17 more
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Disconnected circadian and cell cycles in a tumor-driven cell line
Communicative & Integrative Biology, 2010 Cell division occurs at a specific time of day in numerous species, suggesting that the circadian and cell cycles are coupled in vivo. By measuring the cell cycle rhythm in real-time, we recently showed that the circadian and cell cycles are not coupled ...
Julie S. Pendergast +4 more
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Biomedicines, 2022 The host defense derived peptide was assessed in different model systems with increasing complexity employing the highly aggressive NRAS mutated melanoma metastases cell line MUG-Mel2.
Maximiliane Wußmann +9 more
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Storage conditions and passages alter IL-6 secretion in C26 adenocarcinoma cell lines
MethodsX, 2015 The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Diana M. Norden +3 more
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Nanomaterials, 2023 Multidrug resistance (MDR) is the main challenge in cancer treatment. In this sense, we designed transferrin (Tf)-conjugated PLGA nanoparticles (NPs) containing an organoselenium compound as an alternative to enhance the efficacy of cancer therapy and ...
Letícia Bueno Macedo +8 more
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Ablative and Immunostimulatory Effects of Histotripsy Ablation in a Murine Osteosarcoma Model
Biomedicines, 2023 Background: Osteosarcoma (OS) is the most frequently occurring malignant bone tumor in humans, primarily affecting children and adolescents. Significant advancements in treatment options for OS have not occurred in the last several decades, and the ...
Alayna N. Hay +10 more
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Cancer Medicine, 2020 Basic and clinical studies on small bowel adenocarcinoma (SBA) are limited due to the rare nature of this cancer. We established a patient‐derived xenograft (PDX) model from the tumor tissue of an advanced SBA patient with liver and peritoneal metastasis,
Tomoki Yamano +2 more
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