Results 51 to 60 of about 5,658,856 (358)
Journal of Translational MedicineSarcomas, malignant tumors from mesenchymal tissues, exhibit poor prognosis despite advancements in treatment modalities such as surgery, radiotherapy, and chemotherapy, with doxorubicin being a cornerstone treatment.
Young-Eun Cho +4 more
doaj +1 more source
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. [PDF]
, 2019 Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors.
Aran, D +9 more
core +1 more source
A homozygous genome‐edited Sept2‐EGFP fibroblast cell line [PDF]
, 2019 Septins are a conserved, essential family of GTPases that interact with actin, microtubules, and membranes and form scaffolds and diffusion barriers in cells. Several of the 13 known mammalian septins assemble into nonpolar, multimeric complexes that can
Banko, Monika +4 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Fibroblasts cell lines misclassified as cancer cell lines [PDF]
, 2017 Large collections of immortalized cancer cell lines have been widely used as model systems for cancer research and drug discovery. Some of these models however display more fibroblast-like than cancer-like characteristics based on their genetic and genomic characterization. The correct annotation of these cell lines remains a challenge. Here, we report
de Weck, Antoine +2 more
openaire +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
A Role of the Choroid Plexus in Transplantation Therapy
Cell Transplantation, 2005 The choroid plexuses (CPs) play pivotal roles in the most basic aspects of neural function. Some of the roles of the CP include maintaining the extracellular milieu of the brain by actively modulating chemical exchange between the CSF and brain ...
Dwaine F. Emerich +3 more
doaj +1 more source
Molecules, 2020 Cancer is the second leading cause of death globally, and despite the advances in drug development, it is still necessary to develop new plant-derived medicines.
Ngoc Hong Nguyen +6 more
doaj +1 more source
Cell Line Monolayer Tissue Culture FKDL dan Cell Line OL sebagai Media Penumbuh Virus pada Pengembangan Bioteknologi Biomolekuler (Penelitian Eksperimental Laboratoris) [PDF]
, 2012 Cell line sangatlah penting dalam dunia medis, khususnya dibidang diagnosis, produksi vaksin maupun dibidang bioteknologi serta biomolekuler. Berbagai penelitian telah dilakukan untuk tehnik pembuatan Cell Line Monolayer Tissue Culture.
Hasdianah, H. (Hasdianah)
core
The role of miR-24 as a race related genetic factor in prostate cancer. [PDF]
, 2017 The incidence of prostate cancer (PCa) among African-Americans (AfA) is significantly higher than Caucasian-Americans (CaA) but the genetic basis for this disparity is not known.
Dahiya, Rajvir +15 more
core +1 more source