Results 51 to 60 of about 2,773,088 (322)
Establishment of Breast Phyllodes Tumor Cell Lines Preserving the Features of Phyllodes Tumors
BIO Integration, 2023 Breast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors), its clinical outcomes are unpredictable, and malignant PTs often progress rapidly.
Shishi He +11 more
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Glial Cell Lines: An Overview [PDF]
Neurochemical Research, 2010 The importance and essential functions of glial cells in the nervous system are now beginning to be understood and appreciated. Glial cell lines have been instrumental in the elucidation of many of these properties. In this Overview, the origin and properties of most of the existing cell lines for the major glial types: oligodendroglia, astroglia ...
George H. De Vries, Anne I. Boullerne
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Scientific ReportsMetabolic dysfunction-associated steatohepatitis (MASH) is a form of chronic liver inflammation associated with metabolic syndrome, such as obesity and a major cause of hepatocellular carcinoma (HCC).
Sumin Kim +6 more
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Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines
eLife, 2019 The use of misidentified and contaminated cell lines continues to be a problem in biomedical research. Research Resource Identifiers (RRIDs) should reduce the prevalence of misidentified and contaminated cell lines in the literature by alerting ...
Zeljana Babic +6 more
doaj +1 more source
The Comparative Invasiveness of Endometriotic Cell Lines to Breast and Endometrial Cancer Cell Lines
Biomolecules, 2023 Endometriosis is an invasive condition that affects 10% of women (and people assigned as female at birth) worldwide. The purpose of this study was to characterize the relative invasiveness of three available endometriotic cell lines (EEC12Z, iEc-ESCs, tHESCs) to cancer cell lines (MDA-MB-231, SW1353 and EM-E6/E7/TERT) and assess whether the relative ...
Katherine Ellis, Rachael Wood
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Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Effects of simulated microgravity on colorectal cancer organoids growth and drug response
Scientific ReportsCellular and molecular dynamics of human cells are constantly affected by gravity. Alteration of the gravitational force disturbs the cellular equilibrium, which might modify physiological and molecular characteristics. Nevertheless, biological responses
Soon-Chan Kim +6 more
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Establishment and evaluation of a suckling mouse integrin αυβ8 transgenic cho-677 cell line with increased susceptibility to type o/by/cha/2010 foot-and-mouth disease virus [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 Integrin αυβ8 may play an important role in the initial stage of FMDV infection and influence the host specificity and tissue tropism. To study the role of integrin αυβ8 in FMDV infection, a cell line, which stably expressed the suckling mouse αvβ8 ...
Kaiqi LIAN +4 more
doaj +1 more source
Frontiers in Physiology, 2023 The periosteum is a thin tissue surrounding each skeletal element that contains stem and progenitor cells involved in bone development, postnatal appositional bone growth, load-induced bone formation, and fracture repair.
Emily R. Moore +5 more
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