Results 241 to 250 of about 712,102 (304)

Genetic map of the carotid body stem cell niche with focus on the O₂-sensing chemoreceptor cell lineage. [PDF]

Sci Rep
Santamaría-Santiago A, Sobrino V, Luna-Ramírez L, López-Barneo J, Pardal R.   +4 more
europepmc   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

scLTdb: a comprehensive single-cell lineage tracing database. [PDF]

Nucleic Acids Res
Jiang J, Ye X, Kong Y, Guo C, Zhang M, Cao F, Zhang Y, Pei W.   +7 more
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Stereotyped Subclones Revealed by High-Density Single-Cell Lineage Tracing Support Robust Development. [PDF]

Adv Sci (Weinh)
Zhang X, Li Z, Chen J, Yang W, He X, Wu P, Chen F, Zhou Z, Ren C, Shan Y, Wen X, Lyubetsky VA, Rusin LY, Chen X, Yang JR.   +14 more
europepmc   +1 more source

Single-cell lineage tracing techniques in hematology: unraveling the cellular narrative. [PDF]

J Transl Med
Deng LH, Li MZ, Huang XJ, Zhao XY.
europepmc   +1 more source

The CFII components PCF11 and Cbc change subnuclear localization as cells differentiate in an adult stem cell lineage. [PDF]

MicroPubl Biol
Nava I, Fuller MT, Gallicchio L.
europepmc   +1 more source

Advancements in prospective single-cell lineage barcoding and their applications in research. [PDF]

Genome Res
Zhang X, Huang Y, Yang Y, Wang QE, Li L.
europepmc   +1 more source