Results 271 to 280 of about 459,108 (316)

Cell death in the oligodendrocyte lineage

Journal of Neurobiology, 1992
AbstractWe have recently found that about 50% of newly formed oligodendrocytes normally die in the developing rat optic nerve. When purified oligodendrocytes or their precursors are cultured in the absence of serum or added signalling molecules, they die rapidly with the characteristics of programmed cell death.
B A, Barres, I K, Hart, H S, Coles, J F, Burne, J T, Voyvodic, W D, Richardson, M C, Raff   +6 more
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The evolution of cell lineage in nematodes

Development, 1994
ABSTRACT The invariant development of free-living nematodes combined with the extensive knowledge of Caenorhabditis elegans developmental biology provides an experimental system for an analysis of the evolution of developmental mechanisms. We have collected a number of new nematode species from soil samples.
Sommer, R. ; https://orcid.org/0000-0003-1503-7749, Carta, L., Sternberg, P.   +2 more
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Chimaeras and Cell Lineage in Development

Nature, 1972
CHIMAERAS (or “allophenic individuals”) let us see the pedigree of cells. For instance, a blastocyst compounded from a black-coated-mouse embryo and a white-coated-mouse embryo may develop into a striped or piebald adult mouse1. In other adult tissues, other markers (such as isozymes) reveal a similar conglomerate of two cell types2.
J H, Lewis, D, Summerbell, L, Wolpert
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Cell differentiation lineage in the prostate

Differentiation, 2001
Prostatic epithelium consists mainly of luminal and basal cells, which are presumed to differentiate from common progenitor/stem cells. We hypothesize that progenitor/stem cells are highly concentrated in the embryonic urogenital sinus epithelium from which prostatic epithelial buds develop.
Y, Wang, S, Hayward, M, Cao, K, Thayer, G, Cunha   +4 more
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Stem cells of the melanocyte lineage

Cancer Biomarkers, 2007
Melanocytes are pigment-producing cells responsible for coloration of skin and hair. Studies using mouse models have allowed identification of putative melanocyte stem cells within the hair follicle and understanding of hair graying caused by abnormal melanocyte stem cell maintenance. The malignant transformation of melanocytes results in melanoma, the
Kristina, Buac, William J, Pavan
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Cell lineage in lymphoproliferative disease

The American Journal of Medicine, 1983
Surface marker techniques have made a major contribution to the understanding and classification of lymphoproliferative disorders by permitting the determination of B- and T-cell lineage. The frequent malignant proliferations of B lymphocytes are identified by the presence of surface immunoglobulin of a single light-chain type; Ia-like (HLA-DR) antigen
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Forcing cells to change lineages

Nature, 2009
The ability to produce stem cells by induced pluripotency (iPS reprogramming) has rekindled an interest in earlier studies showing that transcription factors can directly convert specialized cells from one lineage to another. Lineage reprogramming has become a powerful tool to study cell fate choice during differentiation, akin to inducing mutations ...
Thomas, Graf, Tariq, Enver
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The role of cell lineage in development

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985
Abstract Studies of the role of cell lineage in development began in the latter part of the 19th century, fell into decline in the early part of the 20th, and were revived about 20 years ago. This recent revival was accompanied by the introduction of new and powerful analytical techniques.
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Cell lineage and segmentation in the leech

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985
Abstract Segments in the leech arise by the proliferation of longitudinally arrayed bandlets of blast cells derived from ten identifiable embryonic stem cells, two M, two N, four O /P and two Q teloblasts. In each bandlet, older blast cells lie ahead of those born later.
D A, Weisblat, M, Shankland
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Cell lineage in the cerebral cortex

Development, 1991
Abstract We have studied cell lineage in the rat cerebral cortex using retroviral mediated gene transfer. By this method, a marker gene is inserted into dividing precursor cells such that their fate can be followed. We have applied this technique to two types of experiment.
Price, J, Williams, B, Grove, E
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