Results 41 to 50 of about 7,324,993 (258)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cell Migration Research Based on Organ-on-Chip-Related Approaches

open access: yesMicromachines, 2017
Microfluidic devices have been widely used for cell migration research over the last two decades, owing to their attractive features in cellular microenvironment control and quantitative single-cell migration analysis.
Xiaoou Ren, David Levin, Francis Lin
doaj   +1 more source

Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells

open access: yesCell Adhesion & Migration, 2020
DDR1 is a receptor tyrosine kinases for collagen and an adverse prognostic factor in primary and metastatic tumors.Despite this, DDR1 signaling and its functional consequences in tumor development remain unclear.
Irene Romayor   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The migration-security nexus. International migration and security before and after 9/11 [PDF]

open access: yes, 2003
Faist T. The migration-security nexus. International migration and security before and after 9/11. COMCAD Arbeitspapiere - working papers, 9.
Thomas Faist, Faist, Thomas
core   +1 more source

Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway

open access: yesCell Adhesion & Migration, 2020
A decrease in oxygen concentration is a hallmark of inflammatory reactions resulting from infection or homeostasis disorders. Mast cells interact with extracellular matrix and other cells by adhesion receptors.
Joanna Pastwińska   +4 more
doaj   +1 more source

Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells

open access: yesCell Adhesion & Migration, 2021
Microtubules (MTs) control cell shape and intracellular cargo transport. The role of MT turnover in the migration of slow-moving cells through endothelial barriers remains unclear.
Francesco Roncato   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Jahrbuch Migration und Gesellschaft / Yearbook Migration and Society 2020/2021 [PDF]

open access: yes, 2021
Migration is not a state of emergency, but a basic existential experience of humanity. It shapes contemporary societies by challenging established orders, creating transnational spaces beyond national hegemonies, creating new economies, influencing urban

core  

Mast cell tryptase enhances wound healing by promoting migration in human bronchial epithelial cells [Elektronisk resurs]

open access: yes, 2021
Epithelial damage and increase of intraepithelial mast cells (MC) are characteristics of asthma. The role of MC mediator tryptase and the protease-activated receptor-2 (PAR2) on epithelial wound healing is not fully investigated. Stimulation of bronchial
Andersson, Cecilia,   +7 more
core   +1 more source

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