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Cell migration at a glance [PDF]
Journal of Cell Science, 2005 Cell migration is a fundamental process, from simple, uni-cellular organisms such as amoeba, to complex multi-cellular organisms such as mammals. Whereas its main functions comprise mating and the search for food in simple organisms ([Manahan et al., 2004][1]), complexity brings a requirement ...
Miguel, Vicente-Manzanares +2 more
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Class I Myosins, molecular motors involved in cell migration and cancer
Cell Adhesion & Migration, 2022 Class I Myosins are a subfamily of motor proteins with ATPase activity and a characteristic structure conserved in all myosins: A N-Terminal Motor Domain, a central Neck and a C terminal Tail domain. Humans have eight genes for these myosins.
Juan D. Diaz-Valencia +4 more
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Translational Oncology, 2019 AIM: Transfer of exosomes (Exo) miRNA was described interfering with tumor progression. We here explored for claudin7 (cld7) and EpCAM (EpC), cancer-initiating-cell markers in colorectal and pancreatic cancer, the efficacy of Exo loading with miRNA and ...
Daisuke Kyuno +4 more
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Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst
Cell Reports, 2015 The pluripotent epiblast (EPI) is the founder tissue of almost all somatic cells. EPI and primitive endoderm (PrE) progenitors arise from the inner cell mass (ICM) of the blastocyst-stage embryo. The EPI lineage is distinctly identified by its expression
Panagiotis Xenopoulos +4 more
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Cell Adhesion & Migration, 2022 To investigate a novel function of Dipterocarpus tuberculatus on focal cell adhesion stimulation, alterations to the regulation of focal cell adhesion-related factors were analyzed in NHDF cells and a calvarial defect rat model after treatment with ...
Su Jin Lee +9 more
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Imaging of cell migration [PDF]
The EMBO Journal, 2006 Cell migration is an essential process during many phases of development and adult life. Cells can either migrate as individuals or move in the context of tissues. Movement is controlled by internal and external signals, which activate complex signal transduction cascades resulting in highly dynamic and localised remodelling of the cytoskeleton, cell ...
Dirk, Dormann, Cornelis J, Weijer
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Cell Adhesion & Migration, 2023 The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis remains unclear. Here, we confirmed that LL-37 expression enhanced endothelial-mesenchymal transition (EMT), migration and invasion in HCC cells.
Huidan Zhang +5 more
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PLoS Computational Biology, 2020 Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D) cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (ECM), mechanically probe the ECM and contract in order to displace ...
Tommy Heck +5 more
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Scribble, Lgl1, and myosin IIA interact with α-/β-catenin to maintain epithelial junction integrity
Cell Adhesion & Migration, 2023 E-cadherin-catenin complex together with the cytoskeleton, builds the core of Adherens junctions (AJs). It has been reported that Scribble stabilizes the coupling of E-cadherin with catenins promoting epithelial cell adhesion, but the mechanism remains ...
Maha Abedrabbo +4 more
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Cell Adhesion & Migration, 2023 Cutaneous melanoma is a cancer with a very poor prognosis mainly because of metastatic dissemination and therefore a deregulation of cell migration. Current therapies can benefit from complementary medicines as supportive care in oncology.
Camille Fuselier +7 more
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