Results 21 to 30 of about 14,513,312 (335)
Regulation of P53 signaling in breast cancer by the E3 ubiquitin ligase RNF187
Cell Death and Disease, 2022 The tumor suppressor P53 plays critical role in preventing cancer. P53 is rarely mutated and remains functional in luminal-type breast cancer(1).
Xin Li +13 more
doaj +1 more source
Blood Advances, 2017 : CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function on these cells remains elusive.
Dina B. AbuSamra +8 more
doaj +1 more source
MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]
, 2013 Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Preziosi, Luigi, Scianna, Marco
core +1 more source
Cytoskeletal Crosstalk in Cell Migration.
Trends in Cell Biology, 2020 Cell migration is a highly dynamic process driven by the cytoskeleton, which mainly comprises the actin microfilaments, microtubules, and intermediate filaments.
Shailaja Seetharaman +1 more
semanticscholar +1 more source
Spectrin binding motifs regulate Scribble cortical dynamics and polarity function
eLife, 2015 The tumor suppressor protein Scribble (SCRIB) plays an evolutionary conserved role in cell polarity. Despite being central for its function, the molecular basis of SCRIB recruitment and stabilization at the cell cortex is poorly understood.
Batiste Boëda +1 more
doaj +1 more source
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]
, 2017 T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc +10 more
core +3 more sources
Collective cell migration: Implications for wound healing and cancer invasion. [PDF]
, 2013 During embryonic morphogenesis, wound repair and cancer invasion, cells often migrate collectively via tight cell-cell junctions, a process named collective migration.
He, Yong +3 more
core +2 more sources
The Journal of Experimental Medicine, 1967 The preceding studies have established the following points: Intrathymic labeling of thymic lymphocytes provides an adequate marker system to detect the migration of thymus cells to peripheral lymphoid sites. In the newborn, this comprises a major portion of the total lymphocyte population in lymph nodes and spleen.
openaire +2 more sources
Physical Models of Collective Cell Migration [PDF]
Annual Review of Condensed Matter Physics, 2019 Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here, we provide a physical perspective of the mechanisms underlying collective cell migration. We begin with a catalog of the cell–cell
Ricard Alert, X. Trepat
semanticscholar +1 more source
An end-to-end software solution for the analysis of high-throughput single-cell migration data [PDF]
, 2017 The systematic study of single-cell migration requires the availability of software for assisting data inspection, quality control and analysis. This is especially important for high-throughput experiments, where multiple biological conditions are tested
Ampe, Christophe +5 more
core +2 more sources