Results 31 to 40 of about 7,324,993 (258)
Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst
Cell Reports, 2015 The pluripotent epiblast (EPI) is the founder tissue of almost all somatic cells. EPI and primitive endoderm (PrE) progenitors arise from the inner cell mass (ICM) of the blastocyst-stage embryo. The EPI lineage is distinctly identified by its expression
Panagiotis Xenopoulos +4 more
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Cell Adhesion & Migration, 2023 The LMNA gene encoding lamin A/C is amplified in some clear cell renal cell carcinoma (ccRCC) samples. Our data showed that depletion of the tumor suppressor PBRM1 can upregulate lamin A/C levels, and lamin A/C could interact with PBRM1.
Hui Xin +8 more
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Studying fibroblast growth factor (FGF) mediated cell migration in "Drosophila" larval air sacs [PDF]
, 2005 Invertebrates and vertebrates use FGF signaling in many developmental processes. Mesoderm formation, limb outgrowth but also the development of the vascular system and the lung rely on FGF ligands.
Cabernard, Clemens
core +1 more source
Cell Adhesion & Migration, 2023 MARCKS is an actin and PIP2-binding protein that plays an essential role in neutrophil migration and adhesion; however, the molecular details regarding MARCKS function in these processes remains unclear. Neutrophil adhesion and migration also require the
Haleigh Conley +4 more
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Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes [PDF]
, 2009 In normal T cell progenitors, phosphoinositide-dependent kinase l (PDK1)-mediated phosphorylation and activation of protein kinase B (PKB) is essential for the phosphorylation and inactivation of Foxo family transcription factors, and also controls T ...
Feijoo, C. +20 more
core +2 more sources
PLoS Computational Biology, 2020 Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D) cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (ECM), mechanically probe the ECM and contract in order to displace ...
Tommy Heck +5 more
doaj +1 more source
Frontiers in Immunology, 2015 Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is ...
Qianqian eZhang +2 more
doaj +1 more source
The functions of kinesin and kinesin-related proteins in eukaryotes
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Cell Adhesion & Migration, 2020 To elucidate the underlying mechanism of secretory leukocyte protease inhibitor (SLPI)-induced cell migration, we compared SLPI-deleted human gingival carcinoma Ca9-22 (ΔSLPI) cells and original (wild-type: wt) Ca9-22 cells using several microscopic ...
Yusuke Mizutani +6 more
doaj +1 more source