Results 51 to 60 of about 1,804,531 (255)
The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells
Neoplasia: An International Journal for Oncology Research, 2005 Glioblastoma multiforme is extraordinarily aggressive due to the propensity of cells to migrate away from the tumor core into the surrounding normal brain.
Christopher A. Lipinski +7 more
doaj +1 more source
Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway
Cell Adhesion & Migration, 2020 A decrease in oxygen concentration is a hallmark of inflammatory reactions resulting from infection or homeostasis disorders. Mast cells interact with extracellular matrix and other cells by adhesion receptors.
Joanna Pastwińska +4 more
doaj +1 more source
Modelling cell movement and chemotaxis pseudopod based feedback [PDF]
, 2011 A computational framework is presented for the simulation of eukaryotic cell migration and chemotaxis. An empirical pattern formation model, based on a system of non-linear reaction-diffusion equations, is approximated on an evolving cell boundary using ...
Insall, Robert H. +3 more
core +1 more source
Cell ReportsSummary: Glioblastoma (GBM), the most aggressive primary brain tumor, is marked by high invasiveness that enables resistance to current therapies. Single-cell RNA sequencing analysis reveals that elevated expression of glial intermediate filament (IF ...
Emma J. van Bodegraven +18 more
doaj +1 more source
Cell Adhesion & Migration, 2020 Cell-extracellular matrix interactions, or focal adhesions (FA), are crucial for tissue homeostasis but are also implicated in cancer. Integrin-Linked Kinase (ILK) is an abundantly expressed FA protein involved in multiple signaling pathways.
Katerina Tsirtsaki, Vasiliki Gkretsi
doaj +1 more source
Transplantation stimulates interstitial cell migration in hydra [PDF]
, 1990 Migration of interstitial cells and nerve cell precursors was analyzed in Hydra magnipapillata and Hydra vulgaris (formerly Hydra attenuata). Axial grafts were made between [3H]thymidine-labeled donor and unlabeled host tissue. Migration of labeled cells
Bosch +10 more
core +1 more source
Supracellular migration – beyond collective cell migration [PDF]
Journal of Cell Science, 2019 ABSTRACT Collective cell migration is a highly complex process in which groups of cells move together. A fundamental question is how cell ensembles can migrate efficiently. In some cases, the group is no more than a collection of individual cells.
Adam Shellard, Roberto Mayor
openaire +3 more sources
Collective cell durotaxis emerges from long-range intercellular force transmission [PDF]
, 2016 The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated constituent cells did not. This
Conte, V +10 more
core +2 more sources
Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer. [PDF]
, 2017 Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown.
Barrett, John W +17 more
core +1 more source
Cell Adhesion & Migration, 2021 Microtubules (MTs) control cell shape and intracellular cargo transport. The role of MT turnover in the migration of slow-moving cells through endothelial barriers remains unclear.
Francesco Roncato +3 more
doaj +1 more source