Results 61 to 70 of about 551,941 (324)

Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures

, 2019
Here, using an integrative experimental and computational approach, Imle et al. show how cell motility and density affect HIV cell-associated transmission in a three-dimensional tissue-like culture system of CD4+ T cells and collagen, and how different ...
Ales, J., Carrillo-Bustamante, P., Fackler, O., Fehr, J., Godinez, W., Graw, F., Hamprecht, F., Imle, A., Kumberger, P., Müller, B., Ritter, C., Rohr, K., Schmidt, P., Schnellbächer, N., Schwarz, U.   +14 more
core   +2 more sources

Myosin VI in the nucleolus of neurosecretory PC12 cells: its involvement in the maintenance of nucleolar structure and ribosome organization

Frontiers in Physiology
We have previously shown that unconventional myosin VI (MVI), a unique actin-based motor protein, shuttles between the cytoplasm and nucleus in neurosecretory PC12 cells in a stimulation-dependent manner and interacts with numerous proteins involved in ...
Jolanta Nowak, Robert Lenartowski, Robert Lenartowski, Katarzyna Kalita, Lilya Lehka, Olena Karatsai, Marta Lenartowska, Marta Lenartowska, Maria Jolanta Rędowicz   +8 more
doaj   +1 more source

Colony Expansion of Socially Motile Myxococcus xanthus Cells Is Driven by Growth, Motility, and Exopolysaccharide Production. [PDF]

PLoS Computational Biology, 2016
Myxococcus xanthus, a model organism for studies of multicellular behavior in bacteria, moves exclusively on solid surfaces using two distinct but coordinated motility mechanisms.
Pintu Patra, Kimberley Kissoon, Isabel Cornejo, Heidi B Kaplan, Oleg A Igoshin   +4 more
doaj   +1 more source

Squirmer hydrodynamics near a periodic surface topography

Frontiers in Cell and Developmental Biology, 2023
The behaviour of microscopic swimmers has previously been explored near large-scale confining geometries and in the presence of very small-scale surface roughness.
Kenta Ishimoto, Eamonn A. Gaffney, David J. Smith   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Atomic Force Microscopy of height fluctuations of fibroblast cells [PDF]

, 2002
We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope (AFM) under physiological conditions. Correlation between these fluctuations and lateral cellular motility can be observed.
A. Czirók, B. Hegedös, Bálint Szabó, C. Pasternak, C. Rotsch, C.A. Shönenberger, Ch. Rotsch, Ch.S. Peskin, Dávid Selmeczi, E. Henderson, Emília Madarász, F. Jülicher, G.G. Borisy, H. Chen, H. Haga, H.J. Butt, J. Domke, K. Yasuda, L. Mahadevan, L.M. Machesky, M. Bornens, M. Lekka, M.U. Ehrengruber, Noémi Rozlosnik, O.J. Pletjushkina, S.W. Schneider, T. Duke, T.A.J. Duke, U.G. Hofmann, V. Parpura, Zs. Környei, Zsuzsanna Környei   +31 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Myxococcus xanthus gliding motors are elastically coupled to the substrate as predicted by the focal adhesion model of gliding motility

, 2014
Myxococcus xanthus is a model organism for studying bacterial social behaviors due to its ability to form complex multi-cellular structures. Knowledge of M.
Balagam, Rajesh, Czerwinski, Fabian, Igoshin, Oleg A., Kaplan, Heidi B., Litwin, Douglas B., Shaevitz, Joshua W., Sun, Mingzhai   +6 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Tracing blastomere fate choices of early embryos in single cell culture [PDF]

, 2010
Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li, Haobin Zhao, Jianxin Song, Meisheng Yi, Mingyou Li, Ni Hong, Rong Liu, Ruowen Ge, Yan Yan, Yongming Yuan, Yunhan Hong, Zhendong Li   +11 more
core   +1 more source