Results 101 to 110 of about 7,491,510 (261)

Energy substrate supplementation increases ATP levels and is protective to PD neurons

Current Research in Pharmacology and Drug Discovery
Alteration of mitochondrial metabolism by various mutations or toxins leads to various neurological conditions. Age-related changes in energy metabolism could also play the role of a trigger for neurodegenerative disorders.
Andrey Y. Vinokurov, Marina Y. Pogonyalova, Larisa Andreeva, Andrey Y. Abramov, Plamena R. Angelova   +4 more
doaj   +1 more source

Translation and validation of the Pediatric Daytime Sleepiness Scale (PDSS) into Brazilian Portuguese

Jornal de Pediatria, 2016
Objective: The aim of this study was to translate and validate the Pediatric Daytime Sleepiness Scale (PDSS) into Brazilian Portuguese. Methods: The translation/validation process was carried out through translation, back translation, technical review ...
Érico P.G. Felden, Joana D. Carniel, Rubian D. Andrade, Andreia Pelegrini, Tâmile S. Anacleto, Fernando M. Louzada   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death

Frontiers in Immunology, 2018
Amyotrophic Lateral Sclerosis (ALS) is a group of neurodegenerative disorders that featured with the death of motor neurons, which leads to loss of voluntary control on muscles.
Zhengzhao Liu, Zhengzhao Liu, Zhengzhao Liu, Zhengzhao Liu, Hongming Li, Hongming Li, Chungu Hong, Menglu Chen, Menglu Chen, Tao Yue, Tao Yue, Chunyuan Chen, Zhenxing Wang, Qing You, Qing You, Chuanyin Li, Chuanyin Li, Qinjie Weng, Hui Xie, Hui Xie, Hui Xie, Hui Xie, Hui Xie, Ronggui Hu, Ronggui Hu   +24 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Minutes of the New Unity Movement, South Peninsula Branch, meeting held on 27 September 2009

, 2009
Minutes of the New Unity Movement, South Peninsula Branch, meeting held on Sunday, 27 September ...
New Unity Movement
core  

Quantum dots modulate intracellular Ca2+ level in lung epithelial cells

International Journal of Nanomedicine, 2017
Huijuan Yin,1 Jacopo M Fontana,1 Johan Solandt,1,2 Johnny Israelsson Jussi,1 Hao Xu,1 Hjalmar Brismar,1 Ying Fu1 1Section of Cellular Biophysics, Department of Applied Physics, Royal Institute of Technology (KTH), Science for Life Laboratory, Solna ...
Yin HJ, Fontana JM, Solandt J, Jussi JI, Xu H, Brismar H, Fu Y   +6 more
doaj  

RNA transport during TMV cell-to-cell movement

Frontiers in Plant Science, 2012
Studies during the last twenty-five years have provided increasing evidence for the ability of plants to support the cell-to-cell and systemic transport of RNA molecules and that this process plays a role in plant development and in the systemic ...
Eduardo José ePeña, Manfred eHeinlein, Manfred eHeinlein   +2 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Cdc42-mediated tubulogenesis controls cell specification. [PDF]

, 2009
SummaryUnderstanding how cells polarize and coordinate tubulogenesis during organ formation is a central question in biology. Tubulogenesis often coincides with cell-lineage specification during organ development. Hence, an elementary question is whether
Greiner, Thomas, Johansson, Jenny, Semb, Tor Henrik, Wolfhagen Sand, Fredrik,, Greiner, Thomas Uwe, Kesavan, Gokul,, Brakebusch, Cord, Greiner, Thomas,, Sand, Fredrik Wolfhagen, Johansson, Jenny,, Johansson, Jenny Kristina, Kobberup, Sune, Wolfhagen Sand, Fredrik, Kobberup, Sune,, Wu, Xunwei, Semb, Henrik, Semb, Henrik,, Lund University., Kesavan, Gokul   +18 more
core   +1 more source