Results 11 to 20 of about 827,170 (307)
Genome-Directed Cell Nucleus Assembly [PDF]
Biology, 2022 The cell nucleus is frequently considered a cage in which the genome is placed to protect it from various external factors. Inside the nucleus, many functional compartments have been identified that are directly or indirectly involved in implementing ...
Sergey V. Razin, Sergey V. Ulianov
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Mechanobiology of the cell nucleus [PDF]
APL Bioengineering, 2022 Jan Lammerding +2 more
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The Material Properties of the Cell Nucleus: A Matter of Scale [PDF]
Cells, 2023 Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules.
Maud Hertzog, Fabian Erdel
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Lamin A/C and PI(4,5)P2—A Novel Complex in the Cell Nucleus [PDF]
CellsLamins, the nuclear intermediate filaments, are important regulators of nuclear structural integrity as well as nuclear functional processes such as DNA transcription, replication and repair, and epigenetic regulations.
Sara Escudeiro-Lopes +3 more
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Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome [PDF]
Cells, 2023 Down syndrome (DS) is a genetically-based disease based on the trisomy of chromosome 21 (Hsa21). DS is characterized by intellectual disability in association with several pathological traits among which early aging and altered motor coordination are ...
Chiara Rita Inguscio +4 more
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The effect of nucleus size on the cell dose in targeted radionuclide therapy – A monte carlo study
Journal of Medical Signals and Sensors, 2020 Background: Nowadays, the use of radiopharmaceuticals in medicine is unavoidable. Depending on the distribution of the radiopharmaceutical in the cells, the nucleus absorbed dose changes by the variations in their geometry size.
Ebrahim Kouhkan +2 more
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In invasion assays, the breast cancer cell nucleus leads the way [PDF]
BMC Research Notes, 2020 Objective Cancer cell metastasis determines disease prognosis. During cancer cell metastasis, the cancer cell and the cancer cell nucleus have to undergo extreme shape changes.
Malte Renz
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Mitochondrial Factors in the Cell Nucleus. [PDF]
Int J Mol Sci, 2023 The origin of eukaryotic organisms involved the integration of mitochondria into the ancestor cell, with a massive gene transfer from the original proteobacterium to the host nucleus. Thus, mitochondrial performance relies on a mosaic of nuclear gene products from a variety of genomes.
González-Arzola K, Díaz-Quintana A.
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Mitochondrial TFAM as a Signaling Regulator between Cellular Organelles: A Perspective on Metabolic Diseases [PDF]
Diabetes & Metabolism Journal, 2021 Tissues actively involved in energy metabolism are more likely to face metabolic challenges from bioenergetic substrates and are susceptible to mitochondrial dysfunction, leading to metabolic diseases.
Jin-Ho Koh +3 more
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Cells, 2022 The focal adhesion protein Vinculin (VCL) is ascribed to various cytoplasmic functions; however, its nuclear role has so far been ambiguous. We observed that VCL localizes to the nuclei of mouse primary spermatocytes undergoing first meiotic division ...
Jana Petrusová +7 more
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