Searching for a Paradigm Shift in Auger-Electron Cancer Therapy with Tumor-Specific Radiopeptides Targeting the Mitochondria and/or the Cell Nucleus. [PDF]
Fernandes C+9 more
europepmc +1 more source
Functional architecture of the cell nucleus
Harald Herrmann, M. Lienhard Schmitz
openaire +3 more sources
Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron+3 more
wiley +1 more source
Heterogeneous flexibility can contribute to chromatin segregation in the cell nucleus. [PDF]
Girard M+3 more
europepmc +1 more source
Stepwise virus assembly in the cell nucleus revealed by spatiotemporal click chemistry of DNA replication. [PDF]
Gomez-Gonzalez A+7 more
europepmc +1 more source
Combating multidrug resistance and metastasis of breast cancer by endoplasmic reticulum stress and cell-nucleus penetration enhanced immunochemotherapy. [PDF]
Jiang W+13 more
europepmc +1 more source
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau+12 more
wiley +1 more source
Mechanism of exportin retention in the cell nucleus. [PDF]
Kapinos LE+4 more
europepmc +1 more source
The mechanobiology of nuclear phase separation. [PDF]
Lee DSW, Strom AR, Brangwynne CP.
europepmc +1 more source
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas+24 more
wiley +1 more source