Results 211 to 220 of about 845,975 (261)
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Immunocytochemistry of the cell nucleus
Electron Microscopy Reviews, 1990This electron microscopic review addresses in situ immunocytochemistry of the mammalian cell nucleus with special reference to the use of autoantibodies, which are the major source of antinuclear antibodies. The localization of many key nuclear antigens is documented and immunocytochemical data are related to the major functional processes of ...
I, Raska, R L, Ochs, L, Salamin-Michel
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Hyperthermia and the Cell Nucleus
Radiation Research, 1982Recent reviews document that hyperthermic shock inhibits the major nuclear activities, including semiconservative DNA replication (1, 2). These inhibitions may result either from a direct effect of heat on the cell nucleus or as a consequence of changes in other cell compartments [e.g., cell membrane damage (3)].
R L, Warters, J L, Roti Roti
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Trends in Genetics, 1990
Purified DNA can be assembled into structures that closely resemble cell nuclei. The cell-free systems that allow this can be exploited to study assembly pathways for several components of the nucleus. They also offer great opportunities for the experimental analysis of nuclear function.
R A, Laskey, G H, Leno
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Purified DNA can be assembled into structures that closely resemble cell nuclei. The cell-free systems that allow this can be exploited to study assembly pathways for several components of the nucleus. They also offer great opportunities for the experimental analysis of nuclear function.
R A, Laskey, G H, Leno
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2018
Nucleus is a specialized organelle that serves as a control tower of all the cell behavior. While traditional biochemical features of nuclear signaling have been unveiled, many of the physical aspects of nuclear system are still under question. Innovative biophysical studies have recently identified mechano-regulation pathways that turn out to be ...
Dong-Hwee, Kim +2 more
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Nucleus is a specialized organelle that serves as a control tower of all the cell behavior. While traditional biochemical features of nuclear signaling have been unveiled, many of the physical aspects of nuclear system are still under question. Innovative biophysical studies have recently identified mechano-regulation pathways that turn out to be ...
Dong-Hwee, Kim +2 more
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BioEssays, 1988
AbstractThe origin of mitosis and the nuclear envelope were the pivotal processes in the evolutionary origin of the nucleus; they probably occurred in a wall‐less mutant bacterium that evolved a cytoskeleton and phagocytosis about 1500 million years ago.
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AbstractThe origin of mitosis and the nuclear envelope were the pivotal processes in the evolutionary origin of the nucleus; they probably occurred in a wall‐less mutant bacterium that evolved a cytoskeleton and phagocytosis about 1500 million years ago.
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The role of the cell nucleus in mechanotransduction
Current Opinion in Cell Biology, 2020Mechanical forces are known to influence cellular processes with consequences at the cellular and physiological level. The cell nucleus is the largest and stiffest organelle, and it is connected to the cytoskeleton for proper cellular function.
Janota, Cátia +2 more
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Nucleus and nucleus-cytoskeleton connections in 3D cell migration
Experimental Cell Research, 2016Cell migration plays an important role in many physiological and pathological settings, ranging from embryonic development to cancer metastasis. Currently, accumulating data suggest that cells migrating in three-dimensional (3D) environments show well-defined differences compared to their well-established two-dimensional (2D) counterparts.
Lingling, Liu +3 more
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Editorial overview: Cell nucleus: The nucleus: a dynamic organelle
Current Opinion in Cell Biology, 2014The nucleus is perhaps the defining feature of ‘eukaryotes’ (Greek ‘eu-’ (with) ‘-karyon’ (kernel, nucleus)), and the emperor of all eukaryotic organelles in terms of scale and complexity of organization. It is, of course, the repository for almost all genomic information, encoded in DNA sequences wrapped into chromatin as discrete polymer packages ...
Michael P, Rout, Gary H, Karpen
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Protein Synthesis in the Cell Nucleus
Nature, 1955THERE is considerable evidence that the cytoplasm of the cell contains structures capable of carrying out protein synthesis1, and it has been shown in one case2 that formation of protein may be little affected by removal of the nucleus. These findings seem to exclude the appealing hypothesis that the nucleus is the source of the cell's proteins.
D, MAZIA, D M, PRESCOTT
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On the Variability in Cell and Nucleus Shapes
Cells Tissues Organs, 2022Cell morphology is an important regulator of cell function. Many abnormalities in cellular behavior can be discerned from changes in the shape of the cell and its organelles, typically the nucleus. Two major challenges for developing such phenotypic assays are reconstructing 3D surfaces of individual cells and nuclei from confocal images and developing
Anusha Devulapally +3 more
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