Results 181 to 190 of about 6,341,201 (297)

Peptide-Functionalized Gold Nanorods as a Model to Reach the Cell Nucleus: Synthesis and Structural Characterizations in View of Theragnostic Applications. [PDF]

J Phys Chem B
Binelli L, Bertelà F, Amatori S, Lipani D, Battocchio C, Iucci G, Tortora L, Dini V, Grande S, Palma A, Ranaldi M, De Berardis B, Ammendolia MG, Mancini-Terraciano C, Fabbri A, Attili A, Scotognella T, Giordano A, Calcagni ML, Dettin M, Zamuner A, Maraloiu VA, Venditti I.   +22 more
europepmc   +1 more source

Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. [PDF]

Phys Rev Lett, 2021
Zhang Y, Lee DSW, Meir Y, Brangwynne CP, Wingreen NS.   +4 more
europepmc   +1 more source

In focus in Vienna: the cell nucleus [PDF]

Histochemistry and Cell Biology, 2016
Klara, Weipoltshammer, Christian, Schöfer   +1 more
openaire   +2 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

BLoss-DDNet: bending loss and dual-task decoding network for overlapping cell nucleus segmentation of cervical clinical LBC images. [PDF]

Front Artif Intell
Yang G, Chen Z, Guo P, Ma J, Huang J, Jin C, Yang X, Zhao K, Wang Y, Gao Q, Liu C, Wu T, Li Y, Guo Y, Zheng J, Cai X, Yang Y.   +16 more
europepmc   +1 more source

LC3B phosphorylation: autophagosome's ticket for a ride toward the cell nucleus. [PDF]

Autophagy, 2021
Nieto-Torres JL, Encalada SE, Hansen M.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Precision and Accuracy in Quantitative Measurement of Gene Expression from Single-cell/nucleus RNA Sequencing Data. [PDF]

Genomics Proteomics Bioinformatics
Dai R, Zhang M, Chu T, Kopp R, Zhang C, Liu K, Wang Y, Wang X, Chen C, Liu C.   +9 more
europepmc   +1 more source

Modeling stem cell nucleus mechanics using confocal microscopy. [PDF]

Biomech Model Mechanobiol, 2021
Kennedy Z, Newberg J, Goelzer M, Judex S, Fitzpatrick CK, Uzer G.   +5 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source