Results 181 to 190 of about 908,709 (307)

In focus in Vienna: the cell nucleus [PDF]

Histochemistry and Cell Biology, 2016
Klara, Weipoltshammer, Christian, Schöfer   +1 more
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Peptide-Functionalized Gold Nanorods as a Model to Reach the Cell Nucleus: Synthesis and Structural Characterizations in View of Theragnostic Applications. [PDF]

J Phys Chem B
Binelli L, Bertelà F, Amatori S, Lipani D, Battocchio C, Iucci G, Tortora L, Dini V, Grande S, Palma A, Ranaldi M, De Berardis B, Ammendolia MG, Mancini-Terraciano C, Fabbri A, Attili A, Scotognella T, Giordano A, Calcagni ML, Dettin M, Zamuner A, Maraloiu VA, Venditti I.   +22 more
europepmc   +1 more source

Exploring Shared Biomarkers of Myocardial Infarction and Alzheimer's Disease via Single-Cell/Nucleus Sequencing and Bioinformatics Analysis. [PDF]

J Alzheimers Dis, 2023
Xue W, He W, Yan M, Zhao H, Pi J.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

LC3B phosphorylation: autophagosome's ticket for a ride toward the cell nucleus. [PDF]

Autophagy, 2021
Nieto-Torres JL, Encalada SE, Hansen M.
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

BLoss-DDNet: bending loss and dual-task decoding network for overlapping cell nucleus segmentation of cervical clinical LBC images. [PDF]

Front Artif Intell
Yang G, Chen Z, Guo P, Ma J, Huang J, Jin C, Yang X, Zhao K, Wang Y, Gao Q, Liu C, Wu T, Li Y, Guo Y, Zheng J, Cai X, Yang Y.   +16 more
europepmc   +1 more source

Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. [PDF]

Phys Rev Lett, 2021
Zhang Y, Lee DSW, Meir Y, Brangwynne CP, Wingreen NS.   +4 more
europepmc   +1 more source

Functional architecture of the cell nucleus

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008
Schmitz, M. Lienhard, Herrmann, Harald
openaire   +2 more sources