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Origin of the cell nucleus

BioEssays, 1988
AbstractThe origin of mitosis and the nuclear envelope were the pivotal processes in the evolutionary origin of the nucleus; they probably occurred in a wall‐less mutant bacterium that evolved a cytoskeleton and phagocytosis about 1500 million years ago.
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Nucleus and nucleus-cytoskeleton connections in 3D cell migration

Experimental Cell Research, 2016
Cell migration plays an important role in many physiological and pathological settings, ranging from embryonic development to cancer metastasis. Currently, accumulating data suggest that cells migrating in three-dimensional (3D) environments show well-defined differences compared to their well-established two-dimensional (2D) counterparts.
Lingling, Liu   +3 more
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Editorial overview: Cell nucleus: The nucleus: a dynamic organelle

Current Opinion in Cell Biology, 2014
The nucleus is perhaps the defining feature of ‘eukaryotes’ (Greek ‘eu-’ (with) ‘-karyon’ (kernel, nucleus)), and the emperor of all eukaryotic organelles in terms of scale and complexity of organization. It is, of course, the repository for almost all genomic information, encoded in DNA sequences wrapped into chromatin as discrete polymer packages ...
Michael P, Rout, Gary H, Karpen
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On the Variability in Cell and Nucleus Shapes

Cells Tissues Organs, 2022
Cell morphology is an important regulator of cell function. Many abnormalities in cellular behavior can be discerned from changes in the shape of the cell and its organelles, typically the nucleus. Two major challenges for developing such phenotypic assays are reconstructing 3D surfaces of individual cells and nuclei from confocal images and developing
Anusha Devulapally   +3 more
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Influenza A virus and the cell nucleus

Vaccine, 2006
It is over 20 years since the publication of experiments that showed that influenza A virus RNA synthesis takes place in the cell nucleus and that here, the virus subverts the cellular transcription machinery to express and replicate its own single-strand RNA genome. In the years since, our understanding of the organisation of the nucleus has increased
Maria Joao, Amorim, Paul, Digard
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Protein Synthesis in the Cell Nucleus

Nature, 1955
THERE is considerable evidence that the cytoplasm of the cell contains structures capable of carrying out protein synthesis1, and it has been shown in one case2 that formation of protein may be little affected by removal of the nucleus. These findings seem to exclude the appealing hypothesis that the nucleus is the source of the cell's proteins.
D, MAZIA, D M, PRESCOTT
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The Cell Nucleus

JAMA: The Journal of the American Medical Association, 1975
ABSTRACT The ultimate book on the nucleus would require about a million pages just to present the complete base sequence of DNA in a single human nucleus, alphabetically. The three volumes of The Cell Nucleus, of course, make no pretense of offering that kind of information, but they provide a wide range of up-to-date information on the structure and ...
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Functional architecture in the cell nucleus

Biochemical Journal, 2001
The major functions of the cell nucleus, including transcription, pre-mRNA splicing and ribosome assembly, have been studied extensively by biochemical, genetic and molecular methods. An overwhelming amount of information about their molecular mechanisms is available. In stark contrast, very little is known about how these processes are integrated into
M, Dundr, T, Misteli
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Dynamic organization of the cell nucleus

Current Opinion in Genetics & Development, 2007
The dynamic organization of the cell nucleus into subcompartments with distinct biological activities represents an important regulatory layer for cell function. Recent studies provide new insights into the principles, by which nuclear organelles form.
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Calcium signalling in the cell nucleus

Cell Calcium, 1997
The First European Conference on Calcium Signalling in the Cell Nucleus took place in Baia Paraelios, Calabria, Italy, from 4-8 October 1997. It was organized by O. Bachs, E. Carafoli, P. Nicotera and L. Santella (local organizers, G. Bagetta and D. Rotiroti) and attended by about 90 specialists. The scientific content was very high and the discussions
Carafoli E, Nicotera P, Santella L
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