Results 21 to 30 of about 827,170 (307)
PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription
Biomolecules, 2023 The specific post-translational modifications of the C-terminal domain (CTD) of the Rpb1 subunit of RNA polymerase II (RNAPII) correlate with different stages of transcription.
Can Balaban +5 more
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Critical Reviews in Eukaryotic Gene Expression, 2000 The molecular pathways that participate in regulation of gene expression are being progressively unraveled. Extracellular signals, including the binding of extracellular matrix and soluble molecules to cell membrane receptors, activate specific signal transducers that process information inside the cell leading to alteration in gene expression. Some of
S A, Lelièvre +2 more
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Mechanisms governing the accessibility of DNA damage proteins to constitutive heterochromatin
Frontiers in Genetics, 2022 Chromatin is thought to regulate the accessibility of the underlying DNA sequence to machinery that transcribes and repairs the DNA. Heterochromatin is chromatin that maintains a sufficiently high density of DNA packing to be visible by light microscopy ...
Anastasia Roemer +4 more
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MONONUCLEOTIDES OF THE CELL NUCLEUS [PDF]
The Journal of General Physiology, 1957 1. It has been demonstrated by ion exchange chromatography that the cell nucleus contains mononucleotides of adenine, guanine, cytosine, uracil, together with diphosphopyridine nucleotide, and several uridine diphosphate derivatives; the adenine nucleotides predominating in amount.
V G, ALLFREY, A E, MIRSKY, S, OSAWA
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Heterogeneity of Organization of Subcompartments in DSB Repair Foci
Frontiers in Genetics, 2022 Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair ...
Natnael G. Abate, Michael J. Hendzel
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BMJ, 1987 The cell nucleus is the information centre of the cell. It is responsible for copying highly selected regions of the genome into ribonucleic acid (RNA) and for supplying precisely regulated amounts of specific RNA molecules to the cytoplasm, where they are translated into proteins.
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Lipid Microdomains in Cell Nucleus [PDF]
Molecular Biology of the Cell, 2008 It is known that nuclear lipids play a role in proliferation, differentiation, and apoptotic process. Cellular nuclei contain high levels of phosphatidylcholine and sphingomyelin, which are partially linked with cholesterol and proteins to form lipid–protein complexes.
Giacomo, Cascianelli +6 more
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Application of fractal and euclidean methods to differentiate normal and neoplastic thyroid cells
Indian Journal of Medical and Paediatric Oncology, 2020 Context: The differentiated papillary and follicular thyroid neoplasms can be characterized from the notions of fractal and Euclidean geometry to overcome the challenges faced by the pathologist.
Javier Oswaldo Rodriguez +6 more
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The Role of Nuclear Insulin and IGF1 Receptors in Metabolism and Cancer
Biomolecules, 2021 Insulin (InsR) and insulin-like growth factor-1 (IGF1R) receptors mediate the metabolic and growth-promoting actions of insulin and IGF1/IGF2, respectively.
Haim Werner, Rive Sarfstein, Zvi Laron
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Modular Nanotransporters for Nuclear-Targeted Delivery of Auger Electron Emitters
Frontiers in Pharmacology, 2018 This review describes artificial modular nanotransporters (MNTs) delivering their cargos into target cells and then into the nuclei – the most vulnerable cell compartment for most anticancer agents and especially for radionuclides emitting short-range ...
Alexander S. Sobolev +1 more
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