Results 261 to 270 of about 73,798 (303)

Retraction: Enhanced activity of vancomycin by encapsulation in hybrid magnetic nanoparticles conjugated to a cell-penetrating peptide.

open access: yesNanoscale
Zhang W   +7 more
europepmc   +1 more source

Cell-Penetrating Peptides

2021
In this introductory chapter, we first define cell-penetrating peptides (CPPs), give short overview of CPP history and discuss several aspects of CPP classification. Next section is devoted to the mechanism of CPP penetration into the cells, where direct and endocytic internalization of CPP is explained.
Matjaž, Zorko, Ülo, Langel
openaire   +2 more sources

Cell-penetrating peptides

Trends in Pharmacological Sciences, 2000
The established view in cellular biology dictates that the cellular internalization of hydrophilic macromolecules can only be achieved through the classical endocytosis pathway. However, in the past five years several peptides have been demonstrated to translocate across the plasma membrane of eukaryotic cells by a seemingly energy-independent pathway.
M, Lindgren   +3 more
openaire   +2 more sources

The Pharmacokinetics of Cell-Penetrating Peptides

Molecular Pharmaceutics, 2010
Cell-penetrating peptides (CPPs) are able to penetrate the cell membrane carrying cargoes such as peptides, proteins, oligonucleotides, siRNAs, radioisotopes, liposomes, and nanoparticles. Consequently, many delivery approaches have been developed to use CPPs as tools for drug delivery.
Dikran, Sarko   +8 more
openaire   +2 more sources

Predicting cell-penetrating peptides

Advanced Drug Delivery Reviews, 2008
Possibility to predict short peptide sequences capable to penetrate the plasma membrane opens new opportunities for developing peptide based intracellular delivery vectors, called cell-penetrating peptides (CPPs). Predictions of CPPs, however are often based on trial and error and may not always lead to new potent sequences.
Mats, Hansen, Kalle, Kilk, Ulo, Langel
openaire   +2 more sources

Prediction of Cell-Penetrating Peptides

2015
The in silico methods for the prediction of the cell-penetrating peptides are reviewed. Those include the multivariate statistical methods, machine-learning methods such as the artificial neural networks and support vector machines, and molecular modeling techniques including molecular docking and molecular dynamics.The applicability of the methods is ...
Mattias, Hällbrink, Mati, Karelson
openaire   +2 more sources

Home - About - Disclaimer - Privacy