Results 241 to 250 of about 13,797,858 (403)

Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation. [PDF]

Diabetes
Shirakawa J, De Jesus DF, Tsuno T, Basile G, Inoue R, Takatani T, Nishiyama A, Okawa ER, Tamura T, Terauchi Y, Kulkarni RN.   +10 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression. [PDF]

Front Mol Biosci
Ke Q, Li Z, Fan L, Li N, Sun L, Zhao H, Song T.   +6 more
europepmc   +1 more source

MiR-499b-5p inhibits cervical cancer cell proliferation and induces apoptosis by targeting the Notch1 signaling pathway.

, 2021
Hon‐Man Liu, Ji F, Yao Lu, Ssu‐Yuan Chen   +3 more
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Case Image: Mucinous Cystadenoma With Luteal Cell Proliferation During Early Pregnancy. [PDF]

Clin Case Rep
Zahra B, Gulzar S, Fatima F, Ali A, Ali H, Akilimali A.   +5 more
europepmc   +1 more source

FLI-06 suppresses proliferation, induces apoptosis and cell cycle arrest by targeting LSD1 and Notch pathway in esophageal squamous cell carcinoma cells

, 2018
Zhaoming Lu, Yandan Ren, Mengying Zhang, Tianli Fan, Yang Wang, Qi Zhao, Hong‐Min Liu, Wen Zhao, Guiqin Hou   +8 more
openalex   +1 more source

Determination of cell proliferation [PDF]

Clinical Molecular Pathology, 1995
D M, Barnes, C E, Gillett
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Precursor Dendritic Cell Proliferation in Multiple Myeloma: A Precursor to Acute Myeloid Leukemia. [PDF]

Hematol Rep
Reberšek K, Anžej Doma S, Škerget M, Podgornik H.   +3 more
europepmc   +1 more source