Results 201 to 210 of about 12,836,766 (354)

The multifaceted roles of PARP1 in DNA repair and chromatin remodelling

Nature reviews. Molecular cell biology, 2017
A. Chaudhuri, A. Nussenzweig
semanticscholar   +1 more source

Excision Repair in Mammalian Cells [PDF]

Journal of Biological Chemistry, 1995
openaire   +2 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Regulating the balance between GSDMD-mediated pyroptosis and CHMP4B-dependent cell repair attenuates calcium oxalate kidney stone formation. [PDF]

Int J Biol Sci
Yang S, Qi Y, Chen Y, Kong H, Han B, Peng Z, Xu C, Wang B, Chen L, Qi S.   +9 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Dual homologous recombinase-mediated lineage tracing technique: New insights for lung stem cell repair. [PDF]

MedComm (2020)
Wu Y, Xia Z, Wu M.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Ratio of miRNA-29 to miRNA-199 expression coordinates mesenchymal stem cell repair of bleomycin-induced pulmonary injury. [PDF]

Mol Ther Nucleic Acids
Elliot SJ, Anderson-Terhune D, Roos B, Rubio GA, Xia X, Pereira-Simon S, Catanuto P, Civettini G, Hagen ES, Arvanitis C, Shahzeidi S, Glassberg MK.   +11 more
europepmc   +1 more source

RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation. [PDF]

J Cell Biol, 2019
Galino J, Cervellini I, Zhu N, Stöberl N, Hütte M, Fricker FR, Lee G, McDermott L, Lalli G, Bennett DLH.   +9 more
europepmc   +1 more source

Angiogenesis and endothelial cell repair in renal disease and allograft rejection.

Journal of the American Society of Nephrology, 2006
M. Reinders, T. Rabelink, D. Briscoe
semanticscholar   +1 more source