Results 1 to 10 of about 12,978,913 (420)

Acoustic Cell Separation Based on Density and Mechanical Properties. [PDF]

J Biomech Eng, 2020
Density and mechanical properties (e.g., compressibility or bulk modulus) are important cellular biophysical markers. As a result, developing a method to separate cells directly based on these properties benefits various applications including biological
Xie Y, Mao Z, Bachman H, Li P, Zhang P, Ren L, Wu M, Huang TJ.   +7 more
europepmc   +2 more sources

Effective Boundary Correction for Deterministic Lateral Displacement Microchannels to Improve Cell Separation: A Numerical and Experimental Study [PDF]

Biosensors
Particle separation and sorting techniques based on microfluidics have found extensive applications and are increasingly gaining prominence. This research presents the design and fabrication of a microfluidic device for separating cells using ...
Shaghayegh Mirhosseini, Mohammadmahdi Eskandarisani, Aryanaz Faghih Nasiri, Fatemeh Khatami, Akram Mirzaei, Majid Badieirostami, Seyed Mohammad Kazem Aghamir, Mohammadreza Kolahdouz   +7 more
doaj   +2 more sources

Spiral microfluidic devices for cell separation and sorting in bioprocesses. [PDF]

Biomicrofluidics, 2019
Inertial microfluidic systems have been arousing interest in medical applications due to their simple and cost-efficient use. However, comparably small sample volumes in the microliter and milliliter ranges have so far prevented efficient applications in
Herrmann N, Neubauer P, Birkholz M.
europepmc   +2 more sources

Fabrication of Spiral Low-Cost Microchannel with Trapezoidal Cross Section for Cell Separation Using a Grayscale Approach [PDF]

Micromachines, 2023
Trapezoidal cross-sectional spiral microfluidic channels showed high resolution and throughput in cell separation in bio-applications. The main challenges are the complexity and high cost of the fabrication process of trapezoidal cross-sectional channels
Mohamed Adel, Ahmed Allam, Ashraf E. Sayour, Hani F. Ragai, Shinjiro Umezu, Ahmed M. R. Fath El-Bab   +5 more
doaj   +2 more sources

Modeling of Electric Field and Dielectrophoretic Force in a Parallel-Plate Cell Separation Device with an Electrode Lid and Analytical Formulation Using Fourier Series [PDF]

Sensors
Dielectrophoresis (DEP) cell separation technology is an effective means of separating target cells which are only marginally present in a wide variety of cells.
Daiki Nishikawa, Yoshinori Seki, Shigeru Tada   +2 more
doaj   +2 more sources

Pattern Formation of Glioma Cells: Effects of Adhesion [PDF]

EPL (Europhysics Letters) 88, 28006 (2009), 2008
We investigate clustering of malignant glioma cells. \emph{In vitro} experiments in collagen gels identified a cell line that formed clusters in a region of low cell density, whereas a very similar cell line (which lacks an important mutation) did not cluster significantly. We hypothesize that the mutation affects the strength of cell-cell adhesion. We
, C. M. Schneider-Mizell, Deutsch A., Drasdo D., E. A. Chiocca, E. Khain, Huang K., Khain E. Katakowski M. Hopkins S. Szalad A. Jiang F. Chopp M., L. M. Sander, Langer J. S., M. O. Nowicki, Perego C., S. E. Lawler, Tracqui P., Zhdanov V. P.   +14 more
arxiv   +3 more sources

Controlled Scaffold Platform Designs on Nasopharyngeal Carcinoma Cell Separation

IEEE Access, 2021
Nasopharyngeal carcinoma (NPC) is a highly invasive and metastatic disease occurring in the nasopharynx. For early diagnosis or treatment, it is helpful to separate invasive nasopharyngeal carcinoma (NPC43) cells from epithelial (NP460) cells.
Muting Wang, Stella W. Pang
doaj   +1 more source

Numerical simulation of inertial microfluidics: a review

Engineering Applications of Computational Fluid Mechanics, 2023
Since the proposal of inertial microfluidics in 2007, it has been widely used for particle focusing and separation with superior performances. The particle migration behaviour in microchannel is extremely complicated involving various parameters ...
Ruiju Shi
doaj   +1 more source

Isolation of Hepatocytes from Liver Tissue by a Novel, Semi-Automated Perfusion Technology

Biomedicines, 2022
Primary hepatocytes are a major tool in biomedical research. However, obtaining high yields of variable hepatocytes is technically challenging. Most protocols rely on the two-step collagenase perfusion protocol introduced by Per Ottar Seglen in 1976.
Carsten Poggel, Timo Adams, Ronald Janzen, Alexander Hofmann, Olaf Hardt, Elke Roeb, Sarah K. Schröder, Carmen G. Tag, Martin Roderfeld, Ralf Weiskirchen   +9 more
doaj   +1 more source

A Hybrid Spiral Microfluidic Platform Coupled with Surface Acoustic Waves for Circulating Tumor Cell Sorting and Separation: A Numerical Study

Biosensors, 2022
The separation of circulating tumor cells (CTCs) from blood samples is crucial for the early diagnosis of cancer. During recent years, hybrid microfluidics platforms, consisting of both passive and active components, have been an emerging means for the ...
Rana Altay, Murat Kaya Yapici, Ali Koşar   +2 more
doaj   +1 more source