Results 21 to 30 of about 2,922,174 (317)
Frontiers in Cell and Developmental Biology, 2022 To accommodate surplus energy, the adipose tissue expands by increasing adipocyte size (hypertrophy) and number (hyperplasia). The presence of hypertrophic adipocytes is a key characteristic of adipose tissue dysfunction. High-fat diet (HFD) fed C57BL/6J
Claes Fryklund +6 more
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Revisiting the hypothesis of an energetic barrier to genome complexity between eukaryotes and prokaryotes [PDF]
Royal Society Open Science, 2020 The absence of genome complexity in prokaryotes, being the evolutionary precursors to eukaryotic cells comprising all complex life (the prokaryote–eukaryote divide), is a long-standing question in evolutionary biology.
Katsumi Chiyomaru, Kazuhiro Takemoto
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Cell Size: Fat Makes Cells Fat [PDF]
Current Biology, 2017 Nutrients are required for the multiple biosynthetic pathways that result in cell growth, and faster growth due to increased nutrient supply results in larger cell volume. A new study demonstrates that fatty-acid availability limits growth rate and cell envelope capacity, revealing that fatty-acid synthesis is the primary determinant of cell size in ...
Lisa, Willis, Kerwyn Casey, Huang
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Extending the Monod model of microbal growth with memory
Frontiers in Marine Science, 2022 Monod’s model describes the growth of microorganisms using a hyperbolic function of extracellular resource concentration. Under fluctuating or limited resource concentrations this model performs poorly against experimental data, motivating the more ...
Mohammad M. Amirian +2 more
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Cell Size Regulation in Mammalian Cells [PDF]
Cell Cycle, 2007 The regulation of cell growth and proliferation is fundamental for animal development and homeostasis but the mechanisms that coordinate cell growth with cell cycle progression are poorly understood. One possibility is that "cell-size checkpoints" act to delay division until cells have achieved a minimal size or mass however, the existence of such ...
Pedro, Echave +2 more
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What programs the size of animal cells?
Frontiers in Cell and Developmental Biology, 2022 The human body is programmed with definite quantities, magnitudes, and proportions. At the microscopic level, such definite sizes manifest in individual cells - different cell types are characterized by distinct cell sizes whereas cells of the same type ...
Shixuan Liu +8 more
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Cell Cycle, 2007 Cell size plays an indirect role in cell proliferation, as cells must double in size before dividing. Cell size is largely determined by the activity of RNA polymerase I that controls ribosomal RNA synthesis and ribosome biogenesis. The type 1 insulin-like growth factor receptor (IGF-IR) and its docking protein, insulin receptor substrate-1 (IRS-1 ...
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Plant Production Science, 2019 Endoreduplication is the phenomenon by which cells increase their ploidy. Endoreduplication is initiated by the transition from the mitotic cell cycle to the endocycle, in which DNA replication occurs without a subsequent chromosome separation and ...
Hidekazu Kobayashi
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Cellularity of porcine adipose tissue: effects of growth and adiposity
Journal of Lipid Research, 1977 Adipose tissue, from two depots in pigs of three breeding groups with different propensities to fatten, was characterized in terms of weight of the adipose tissue organ, adipose cell number, and mean cell volume as determined by electronic counting of ...
R L Hood, C E Allen
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Cell size, body size and Peto’s paradox
BMC Ecology and Evolution, 2022 AbstractCarcinogenesis is one of the leading health concerns afflicting presumably every single animal species, including humans. Currently, cancer research expands considerably beyond medicine, becoming a focus in other branches of natural science.
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