Results 31 to 40 of about 3,250,985 (308)
Size-dependent increase in RNA Polymerase II initiation rates mediates gene expression scaling with cell size [PDF]
, 2020 Cell size varies during the cell cycle and in response to external stimuli. This requires the tight coordination, or “scaling”, of mRNA and protein quantities with the cell volume in order to maintain biomolecules concentrations and cell density ...
Bowman, Anthony +9 more
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Cell Cycle, 2007 Cell size plays an indirect role in cell proliferation, as cells must double in size before dividing. Cell size is largely determined by the activity of RNA polymerase I that controls ribosomal RNA synthesis and ribosome biogenesis. The type 1 insulin-like growth factor receptor (IGF-IR) and its docking protein, insulin receptor substrate-1 (IRS-1 ...
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The Regulation of Cell Size [PDF]
Cell, 2013 An adult animal consists of cells of vastly different size and activity, but the regulation of cell size remains poorly understood. Recent studies uncovering some of the signaling pathways important for size/growth control, together with the identification of diseases resulting from aberrations in these pathways, have renewed interest in this field ...
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Cell Size Control in Yeast [PDF]
Current Biology, 2012 Cell size is an important adaptive trait that influences nearly all aspects of cellular physiology. Despite extensive characterization of the cell-cycle regulatory network, the molecular mechanisms coupling cell growth to division, and thereby controlling cell size, have remained elusive.
Turner, Jonathan J. +2 more
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mTORC2 controls neuron size and Purkinje cell morphology independent of mTORC1 [PDF]
, 2012 Prenatal brain development is mainly accomplished by extensive proliferation of neuronal precursor cells whereas postnatal brain growth in mammals is mainly mediated by the growth of those post-mitotic nerve cells.
Thomanetz, Venus
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Plant Production Science, 2019 Endoreduplication is the phenomenon by which cells increase their ploidy. Endoreduplication is initiated by the transition from the mitotic cell cycle to the endocycle, in which DNA replication occurs without a subsequent chromosome separation and ...
Hidekazu Kobayashi
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Cellularity of porcine adipose tissue: effects of growth and adiposity
Journal of Lipid Research, 1977 Adipose tissue, from two depots in pigs of three breeding groups with different propensities to fatten, was characterized in terms of weight of the adipose tissue organ, adipose cell number, and mean cell volume as determined by electronic counting of ...
R L Hood, C E Allen
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Cell size, body size and Peto’s paradox
BMC Ecology and Evolution, 2022 AbstractCarcinogenesis is one of the leading health concerns afflicting presumably every single animal species, including humans. Currently, cancer research expands considerably beyond medicine, becoming a focus in other branches of natural science.
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The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth
Frontiers in Cell and Developmental Biology, 2017 Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs.
Suam Gonzalez, Charalampos Rallis
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Fruit shape loci sun, ovate, fs8.1 and their interactions affect seed size and shape in tomato
Frontiers in Plant Science, 2023 Seed size and shape are not only critical for plant reproduction and dispersal, but also important agronomic traits. Tomato fruit shape loci sun, ovate and fs8.1 regulate the morphology of fruit, flower, leaf and stem, and recently their functions in ...
Jie Chen +15 more
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