Results 61 to 70 of about 3,250,985 (308)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Control and maintenance of mammalian cell size

BMC Cell Biology, 2004
Background Conlon and Raff propose that mammalian cells grow linearly during the division cycle. According to Conlon and Raff, cells growing linearly do not need a size checkpoint to maintain a constant distribution of cell sizes.
Cooper Stephen
doaj   +1 more source

Thermal-tolerant potential of ordinary Chlorella pyrenoidosa and the promotion of cell harvesting by heterotrophic cultivation at high temperature

Frontiers in Bioengineering and Biotechnology, 2022
During the heterotrophic cultivation of microalgae, a cooled process against temperature rise caused by the metabolism of exogenous organic carbon sources greatly increases cultivation cost.
Yu-Ren Dai, Die Wang, Yu-Rong Zhu, Kun-Xiao Yang, Ning Jiao, Zhong-Liang Sun, Shi-Kai Wang   +6 more
doaj   +1 more source

A Cell Size Theory of Aging [PDF]

Developmental Cell, 2018
The factors determining longevity of different animals are incompletely defined. In this issue of Developmental Cell, Anzi et al. (2018) show that distinct strategies for postnatal pancreatic growth operate in different mammals and correlate with lifespan, with short-lived species exhibiting increasing pancreatic cell size and long-lived animals ...
Krushna C, Patra, Nabeel, Bardeesy
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

Cell-Size-Dependent Transcription of FLC and Its Antisense Long Non-Coding RNA COOLAIR Explain Cell-to-Cell Expression Variation

, 2022
Single-cell quantification of transcription kinetics and variability promotes a mechanistic understanding of gene regulation. Here, using single-molecule RNA fluorescence in situ hybridization and mathematical modeling, we dissect cellular RNA dynamics ...
Wu, Zhe, Ietswaart, Robert, Howard, Martin, Dean, Caroline, Rosa, Stefanie   +4 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Cell size may affect heat tolerance in Drosophila

, 2019
The dataset contains raw data of cell size, cell number, wing size and survival time of Drosophila melanogaster used for the analyses and to generate figures of the Insect Science paper (https://doi.org/10.1111/1744-7917.12742) by Verspagen, Leiva ...
Verberk, dr. W.C.E.P. (Radboud University) DAI=info:eu-repo/dai/nl/265948576, Leiva, F.P. (Radboud University) DAI=info:eu-repo/dai/nl/424748835, Verspagen, N, Janssen, ing. I.M. (Radboud University) DAI=info:eu-repo/dai/nl/321517466   +3 more
core   +1 more source

Computational and theoretical insights into the homeostatic response to the decreased cell size of midbrain dopamine neurons

Physiological Reports, 2021
Midbrain dopamine neurons communicate signals of reward anticipation and attribution of salience. This capacity is distorted in heroin or cocaine abuse or in conditions such as human mania.
Francisco Arencibia‐Albite, Carlos A. Jiménez‐Rivera   +1 more
doaj   +1 more source