Results 151 to 160 of about 14,964,075 (408)

Survival in cervical cancer with respect to cell type [PDF]

open access: bronze, 1959
W. Budd Wentz, James W. Reagan
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Use of Computational Biochemistry for Elucidating Molecular Mechanisms of Nitric Oxide Synthase

open access: yesComputational and Structural Biotechnology Journal, 2019
Nitric oxide (NO) is an essential signaling molecule in the regulation of multiple cellular processes. It is endogenously synthesized by NO synthase (NOS) as the product of L-arginine oxidation to L-citrulline, requiring NADPH, molecular oxygen, and a ...
Emmanuelle Bignon   +3 more
doaj  

Quorum sensing contributes to activated B cell homeostasis and to prevent autoimmunity [PDF]

open access: yesarXiv, 2012
Maintenance of plasma IgM levels is critical for immune system function and homeostasis in humans and mice. However, the mechanisms that control homeostasis of the activated IgM-secreting B cells are unknown. After adoptive transfer into immune-deficient hosts, B-lymphocytes expand poorly but fully reconstitute the pool of natural IgM-secreting cells ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Calculations of the cell survival rate after irradiating with minibeams of protons and $^{12}$C [PDF]

open access: yesarXiv
The propagation of minibeams of protons and $^{12}$C in a water phantom was modelled with Geant4 v10.3, and the survival probabilities of human salivary gland cells representing healthy and tumour tissues of normal radiosensitivity were calculated with the modified microdosimetric kinetic model.
arxiv  

Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response

open access: yesCell, 2020
Raul Zavaliev   +3 more
semanticscholar   +1 more source

Five-Year Survival and Correlates Among Patients With Advanced Melanoma, Renal Cell Carcinoma, or Non–Small Cell Lung Cancer Treated With Nivolumab

open access: yesJAMA Oncology, 2019
This secondary analysis of the phase 1 CA209-003 clinical trial assesses the 5-year survival and other related factors among patients with advanced melanoma, renal cell carcinoma, or non–small cell lung cancer receiving nivolumab.
S. Topalian   +22 more
semanticscholar   +1 more source

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