Results 91 to 100 of about 7,161,603 (302)

Aspirin, platelet inhibition and cancer prevention

Platelets, 2018
Several lines of evidence are consistent with the hypothesis that activated platelets contribute to colorectal tumorigenesis and metastatization through direct cell–cell interactions and the release of different lipid and protein mediators, and ...
Paola Patrignani, Carlo Patrono
doaj   +1 more source

Human papillomavirus-mediated carcinogenesis and HPV-associated oral and oropharyngeal squamous cell carcinoma. Part 1: Human papillomavirus-mediated carcinogenesis

Head & Face Medicine, 2010
High-risk human papillomavirus (HPV) E6 and E7 oncoproteins are essential factors for HPV-induced carcinogenesis, and for the maintenance of the consequent neoplastic growth.
Khammissa Razia AG, Wood Neil H, Feller Liviu, Lemmer Johan   +3 more
doaj   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Neoplastic transformation induced by carbon ions

, 2006
Neoplastic transformation in vitro can be used as an indicator for risk assessment comparing different radiation types. In this work transformation of CGL1 cells by monoenergetic carbon ions has ben measured and compared to photon ...
P. Hessel, D. Bettega, W. K. Weyrather, P. Calzolari   +3 more
core   +2 more sources

Emerging roles of telomeric chromatin alterations in cancer

Journal of Experimental & Clinical Cancer Research, 2019
Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo   +2 more
doaj   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

MECANISMO DE INFECCIÓN Y TRANSFORMACIÓN NEOPLÁSICA PRODUCIDO POR VIRUS PAPILOMA HUMANO EN EL EPITELIO CERVICAL

Revista Chilena de Obstetricia y Ginecología, 2006
Se presenta una revisión bibliográfica del mecanismo de infección y transformación neoplásica producida por el virus papiloma humano, de alto riesgo oncogénico, en el epitelio cervical.
René Rivera Z, Jorge Delgado D, Vicente Painel P, Raúl Barrero P, Angélica Larraín H   +4 more
doaj  

Cytologic Manifestations of Neoplastic Transformation In Vitro 1

, 1969
SUMMARY-Our objective was to test whether cytologic diagnoses of neoplastic transformation could be made accurately on cultured cells in vitro. Cytologic criteria of malignancy as applied to tissues or exfoliated cells in vivo served as guidelines for ...
Barbara E. Barker, Katherine K. Sanford, Barker, B E, Sanford, K K   +3 more
core  

Iron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation in Vitro Is Reduced with a Protective Amorphous Silica Coating

, 2019
Iron oxide nanoparticles (IONP) have recently surged in production and use in a wide variety of biomedical and environmental applications. However, their potential long-term health effects, including carcinogenesis, are unknown. Limited research suggests
Todd A. Stueckle (1908121), Liying W. Rojanasakul, Raymond Derk (7846250), Yon Rojanasakul (321096), Philip Demokritou, Yon Rojanasakul, Todd A. Stueckle, Tiffany G. Kornberg, Jayme Coyle (7846247), Liying W. Rojanasakul (5760038), Raymond Derk, Philip Demokritou (807278), Tiffany G. Kornberg (4875382), Jayme Coyle   +13 more
core   +1 more source