Results 81 to 90 of about 633,194 (250)

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]

open access: yes, 2008
Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J   +5 more
core  

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

open access: yes, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela   +5 more
core   +1 more source

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.

open access: yesGenes & Development, 2009
Pancreatic ductal adenocarcinoma (PDAC) is characterized by the deregulation of the hedgehog signaling pathway. The Sonic Hedgehog ligand (Shh), absent in the normal pancreas, is highly expressed in pancreatic tumors and is sufficient to induce ...
Olivier Nolan-Stevaux   +6 more
semanticscholar   +1 more source

Radiosensitivity Parameters for Neoplastic Transformations in C3H10T1/2 Cells

open access: yesRadiation Research, 1987
We have evaluated radiosensitivity parameters for cellular transformation from published experimental data on neoplastic transformations induced in C3H10T1/2 cells by BEVALAC ions. The measured RBE values are well reproduced by a track theory calculation using sets of m-target parameters with either m = 2 or m = 3, suggesting a quadratic or cubic ...
Waligorski, M. P. R.   +2 more
openaire   +3 more sources

Histology of non-melanoma skin cancers. An Update [PDF]

open access: yes, 2017
Non-melanoma skin cancer (NMSC) is the most frequently diagnosed cancer in humans. Several different non-melanoma skin cancers have been reported in the literature, with several histologic variants that frequently cause important differential diagnoses ...
Cantisani, Carmen   +4 more
core   +2 more sources

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro

open access: yesMarine Drugs, 2016
Guanidine alkaloids from sponges Monanchora spp. represent diverse bioactive compounds, however, the mechanisms underlying bioactivity are very poorly understood.
Sergey A. Dyshlovoy   +13 more
doaj   +1 more source

Transitional cell carcinoma developing in a bladder diverticulum: Early diagnosis by computed tomography

open access: yesSouth African Journal of Radiology, 2013
Computed tomography confirmed a left-sided narrow neck urinary bladder diverticulum, with wall thickening, in a 56-year-old man. These findings were initially detected on ultrasonographic investigation.
Jeshil R. Shah
doaj   +1 more source

RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]

open access: yes, 2011
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski   +3 more
core   +1 more source

Pleiotropic Role of HSF1 in Neoplastic Transformation

open access: yesCurrent Cancer Drug Targets, 2014
HSF1 (Heat Shock transcription Factor 1) is the main transcription factor activated in response to proteotoxic stress. Once activated, it induces an expression of heat shock proteins (HSPs) which enables cells to survive in suboptimal conditions.
N. Vydra, Agnieszka Toma, W. Widłak
semanticscholar   +1 more source

Nutrigenetika - uloga ishrane i nasleđa u nastanku i sprečavanju malignih bolesti [PDF]

open access: yesVojnosanitetski Pregled, 2004
Radaković Sonja S.   +3 more
doaj   +1 more source

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