Results 71 to 80 of about 294,511 (213)

The impact of molecular alterations and the immune microenvironment on the natural history of Follicular Lymphoma including transformation to Diffuse Large B cell Lymphoma

, 2009
PhDThe natural history of follicular lymphoma is heterogeneous with numerous relapses and remissions over many years. A substantial number of patients suffer an aggressive disease course with death due to disease within 5 years of diagnosis.
Lee, Abigail Mary
core  

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing, Wagener, Nina, Hüsing Johannes, Karin Hoppe-Seyler, Hoppe-Seyler Felix, Peter Schirmacher, Hoppe-Seyler, Karin, Pfitzenmaier, Jesco, Macher-Göppinger, Stephan, Jesco Pfitzenmaier, Hohenfellner, Markus, Hüsing, Johannes, Haferkamp, Axel, Haferkamp Axel, Stephan Macher-Goeppinger, Maria Pritsch, Wagener Nina, Pritsch Maria, Axel Haferkamp, Schirmacher Peter, Nina Wagener, Hoppe-Seyler Karin, Hohenfellner Markus, Felix Hoppe-Seyler, Hoppe-Seyler, Felix, Pfitzenmaier Jesco, Macher-Goeppinger Stephan, Markus Hohenfellner, Pritsch, Maria, Schirmacher, Peter   +29 more
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Iron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation in Vitro Is Reduced with a Protective Amorphous Silica Coating

, 2019
Iron oxide nanoparticles (IONP) have recently surged in production and use in a wide variety of biomedical and environmental applications. However, their potential long-term health effects, including carcinogenesis, are unknown. Limited research suggests
Todd A. Stueckle (1908121), Liying W. Rojanasakul, Raymond Derk (7846250), Yon Rojanasakul (321096), Philip Demokritou, Yon Rojanasakul, Todd A. Stueckle, Tiffany G. Kornberg, Jayme Coyle (7846247), Liying W. Rojanasakul (5760038), Raymond Derk, Philip Demokritou (807278), Tiffany G. Kornberg (4875382), Jayme Coyle   +13 more
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Development of an in vitro model for investigating the properties of human prostate epithelial cells and prostatic carcinoma cells

, 2009
Prostate cell lines were derived from two regions of prostate tissue from the same patient. The objective was to produce cell lines (as a useful in vitro model) from these two different regions which exhibit different properties for carcinoma development.
Weaver, Jennifer
core  

Emerging roles of telomeric chromatin alterations in cancer

Journal of Experimental & Clinical Cancer Research, 2019
Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo   +2 more
doaj   +1 more source

Abstract 1227: Inhibition of the RSK2-ATF1 signaling axis by eriodictyol suppresses neoplastic cell transformation

, 2010
The ribosomal S6 kinase 2 (RSK2), a member of the p90RSK (RSK) family of proteins, is a widely expressed serine/threonine kinase and its activation enhances cell proliferation.
Yong-Yeon Cho, Duo Zheng, Angelo Pugliese, Margarita Malakhova, Zigang Dong, Kangdong Liu, Wei-Ya Ma, Ziming Dong, Jishai Zhang, Zhiwei He, Ke Yao, Ann Bode   +11 more
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MECANISMO DE INFECCIÓN Y TRANSFORMACIÓN NEOPLÁSICA PRODUCIDO POR VIRUS PAPILOMA HUMANO EN EL EPITELIO CERVICAL

Revista Chilena de Obstetricia y Ginecología, 2006
Se presenta una revisión bibliográfica del mecanismo de infección y transformación neoplásica producida por el virus papiloma humano, de alto riesgo oncogénico, en el epitelio cervical.
René Rivera Z, Jorge Delgado D, Vicente Painel P, Raúl Barrero P, Angélica Larraín H   +4 more
doaj  

Bone marrow evaluation in patients with fever of unknown origin

Journal of Pathology of Nepal, 2012
Bone marrow examination is commonly requested investigations in cases of fever of unknown origin, irrespective of alteration in hematological parameters.
A Jha, RC Adhikari, R Sarda
doaj   +1 more source

Neoplastic Transformation and Aberrant Cell–Cell Interactions in Genetic Mosaics oflethal(2)giant larvae (lgl),a Tumor Suppressor Gene ofDrosophila

, 1995
Homozygosity forlethal(2)giant larvae (lgl),a mutation in a tumor suppressor gene ofDrosophila,induces neoplasia of the imaginal discs. To explore the developmental capacities oflglmutant cells, we have investigated their growth and differentiation in ...
Kango, Madhuri, Sinha, Pradip, Agrawal, Namita, Mishra, Arati   +3 more
core   +1 more source

Gli1 mediates lung cancer cell proliferation and sonic hedgehog-dependent mesenchymal cell activation. [PDF]

, 2013
Non-Small-Cell-Lung-Cancer (NSCLC) represents approximately 85% of all lung cancers and remains poorly understood. While signaling pathways operative during organ development, including Sonic Hedgehog (Shh) and associated Gli transcription factors (Gli1 ...
Hennen, Elisabeth, Olga Bermudez, Oliver Eickelberg, Olga Bermudez (410727), Ina Koch (7903), Oliver Eickelberg (153848), Eickelberg, O., Bermudez, O., Koch, I., Lindner, Michael, Elisabeth Hennen, Hennen, E., Koch, Ina, Elisabeth Hennen (410728), Bermudez, Olga, Michael Lindner, Ina Koch, Michael Lindner (383308), Lindner, M., Eickelberg, Oliver   +19 more
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