Results 51 to 60 of about 294,511 (213)

Frequency of spontaneous neoplastic transformation in bystander cells.

, 2013
Neoplastic transformation frequency in the progeny of bystander C3H 10T½ MEFs assayed 10 population doublings after they had been in co-culture with 1 GeV/nucleon iron ion- or sham-irradiated MEFs.
Manuela Buonanno (349029), Sonia M. de Toledo (349031), Edouard I. Azzam (349032)   +2 more
core   +1 more source

Transformation of benign phyllodes to malignant phyllodes tumor

Medicina, 2015
Importance of the problem: Malignant phyllodes tumors are rare fibroepithelial neoplasm in which clinical findings remain insufficient to determine a proper preoperative diagnoses and therefore has an unpredictable clinical outcome for optimal treatment.
Adrienne Pratti Lucarelli, Maria Marta Martins, Maria Antonieta Longo Galvão, José Mendes Aldrighi   +3 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms

eJHaem, 2022
This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a
Siba El Hussein, Mariko Yabe, Wei Wang, Naveen Pemmaraju, Sanam Loghavi, Fatima Zahra Jelloul, Hong Fang, L. Jeffrey Medeiros, W. Richard Burack, Andrew G. Evans, Jane L. Liesveld, John M. Bennett   +11 more
doaj   +1 more source

Radiosensitivity Parameters for Neoplastic Transformations in C3H10T1/2 Cells

Radiation Research, 1987
We have evaluated radiosensitivity parameters for cellular transformation from published experimental data on neoplastic transformations induced in C3H10T1/2 cells by BEVALAC ions. The measured RBE values are well reproduced by a track theory calculation using sets of m-target parameters with either m = 2 or m = 3, suggesting a quadratic or cubic ...
Waligorski, M. P. R., Sinclair, G. L., Katz, Robert   +2 more
openaire   +3 more sources

On the Origin of Pancreatic Endocrine Cells, Proliferation and Neoplastic Transformation

Tumor Biology, 1993
In the adult mouse, pancreatic islets contain four islet cell types: alpha, beta, delta and pancreatic polypeptide cells that synthesize glucagon, insulin, somatostatin and pancreatic polypeptide, respectively. The early progenitor cells to the pancreatic islets are multipotential and coactivate all the islet-specific genes from the time they first ...
openaire   +2 more sources

FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks

Frontiers in Cell and Developmental Biology
PurposeFOS-like antigen 1 (FRA1), encoded by FOSL1, is an inducible subunit of the AP-1 transcription factor complex and regulates gene expression in response to proliferative and environmental cues.
Wuroud Al-Khayyat, Taylor Laframboise, Jessica Dougherty, Marc S. Mendonca, Douglas R. Boreham, Douglas R. Boreham, T. C. Tai, T. C. Tai, T. C. Tai, Christopher Thome, Christopher Thome, Christopher Thome, Sujeenthar Tharmalingam, Sujeenthar Tharmalingam, Sujeenthar Tharmalingam   +14 more
doaj   +1 more source

. Modern concepts on carcinogenesis: the value of insufficiency of malignant cell elimination mechanisms in the tumor progression in case of neoplasia at different localizations [PDF]

Саратовский научно-медицинский журнал, 2016
The article presents the review of contemporary concepts of tumor induction mechanisms applicable for neoplastic transformation, promotion and proliferation.
Chesnokova N.P., Morrison V.V., Barsukov V.Yu., Ponukalina E.M., Agabekov A.l.   +4 more
doaj  

KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis

Nature Communications, 2016
It is unclear whether there is a progenitor/stem cell in the basal layer of the urothelium in the bladder. Here, the authors identify Keratin14 positive cells that can regenerate the bladder in both a natural and injury-induced manner, and following ...
George Papafotiou, Varvara Paraskevopoulou, Eleni Vasilaki, Zoi Kanaki, Nikolaos Paschalidis, Apostolos Klinakis   +5 more
doaj   +1 more source

Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism

iScience, 2020
Summary: Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant ...
Ailiang Zeng, Zhiyun Wei, Rosalia Rabinovsky, Hyun Jung Jun, Rachid El Fatimy, Evgeny Deforzh, Ramil Arora, Yizheng Yao, Shun Yao, Wei Yan, Erik J. Uhlmann, Alain Charest, Yongping You, Anna M. Krichevsky   +13 more
doaj   +1 more source

Tumour-associated immune responses and isolated carcinoembryonic antigen and alpha feto-protein levels related to survival in ovarian cancer patients.

, 1976
The presence of a tumour-associated immune response in 37 patients with ovarian cancer as assessed by blastogenesis (lymphocyte transformation) evoked by ovarian cancer cell extracts, has been correlated with survival following the test.
A M Neville, Neville, AM, Hudson, CN, Poulton, TA, T A Poulton, C N Hudson, McHardy, JE, Curling, OM, O M Curling, Levin, L, J E McHardy, M J Kitau, Kitau, MJ, L Levin   +13 more
core   +1 more source