Results 31 to 40 of about 633,194 (250)

Primary splenic lymphoma on top of intrahepatic splenosis: A unique case report

open access: yesRadiology Case Reports, 2022
Solid organ splenosis is a challenging diagnosis with many atypical imaging features that can overlap with neoplastic masses of the affected organ. We present a sporadic case of intrahepatic splenosis in a 68-year-old woman with transformation into a low-
Moataz Soliman, MD   +4 more
doaj   +1 more source

Equol, a Metabolite of the Soybean Isoflavone Daidzein, Inhibits Neoplastic Cell Transformation by Targeting the MEK/ERK/p90RSK/Activator Protein-1 Pathway*

open access: yesJournal of Biological Chemistry, 2007
Daidzein and genistein are isoflavones found in soybean. Genistein is known to exhibit anticarcinogenic activities and inhibit tyrosine kinase activity.
N. Kang   +7 more
semanticscholar   +1 more source

Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. [PDF]

open access: yesPLoS ONE, 2011
High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation.
Svetlana Vinokurova   +1 more
doaj   +1 more source

A metastatic secretory gastric plasmacytoma with aberrant CD3 expression in a dog [PDF]

open access: yes, 2017
A 10-year-old crossbred dog was presented with a 6-week history of hematemesis, melena, anorexia, and lethargy. Clinical evaluation revealed a gastric mass with a regional lymphadenomegaly as well as a monoclonal gammopathy manifesting as ...
Atherton, Matthew J.   +4 more
core   +1 more source

Neoplastic transformation of breast epithelial cells by genotoxic stress [PDF]

open access: yesBMC Cancer, 2010
Abstract Background Exposure to genotoxic stresses such as radiation and tobacco smoke can cause increased cancer incidence rate as reflected in an in depth meta-analysis of data for women and breast cancer incidence.
Raman Venu   +2 more
openaire   +3 more sources

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

open access: yes, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core   +2 more sources

Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation

open access: yesCell Division, 2008
Mitogenic induction of cyclin D1, the allosteric regulator of CDK4/6, is a key regulatory event contributing to G1 phase progression. Following the G1/S transition, cyclin D1 activation is antagonized by GSK3β-dependent threonine-286 (Thr-286 ...
Diehl J Alan, Pontano Laura L
doaj   +1 more source

5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: Evidence

open access: yesBladder Cancer, 2020
BACKGROUND: Androgen receptor (AR) activation has been implicated in the pathogenesis of urothelial cancer. However, it remains controversial whether 5α-reductase inhibitors (5α-RIs), which are known for blocking the conversion of testosterone to the ...
Yujiro Nagata   +4 more
doaj   +1 more source

Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report

open access: yesDermatology Reports, 2021
Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical regions.
Walter Belda Jr.   +3 more
doaj   +1 more source

Mechanisms of radiation-induced neoplastic cell transformation [PDF]

open access: yes, 1984
Studies with cultured mammalian cells demonstrated clearly that radiation can transform cells directly and can enhance the cell transformation by oncogenic DNA viruses. In general, high-LET heavy-ion radiation can be more effective than X and gamma rays in inducing neoplastic cell transformation.
Yang, T. C. H., Tobias, C. A.
openaire   +2 more sources

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