Mechanisms of radiation-induced neoplastic cell transformation [PDF]
, 1984 Studies with cultured mammalian cells demonstrated clearly that radiation can transform cells directly and can enhance the cell transformation by oncogenic DNA viruses. In general, high-LET heavy-ion radiation can be more effective than X and gamma rays in inducing neoplastic cell transformation.
Yang, T. C. H., Tobias, C. A.
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Radiation-induced neoplastic transformation of human cells. [PDF]
Scanning microscopy, 1993 Ionizing radiation can induce cancers in humans and animals and can cause in vitro neoplastic transformation of various rodent cell systems. However, numerous attempts to achieve neoplastic transformation of human cells by radiation have generally proven unsuccessful.
Rhim, J. S. +4 more
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Elastic Moduli of Cells undergoing Neoplastic Transformation [PDF]
Biophysical Journal, 2013 Using an Atomic Force Microscope (AFM) with a 5.3 um diameter spherical probe we determined the elastic modulus of human mammary epithelial cells (HMEC) as they undergo neoplastic transformation from normal to immortal, tumorigenic, and finally metastatic. We did the measurements over both cytoplasmic and nuclear regions; and as a function of the cells
Guo, Xinyi +2 more
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Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]
, 1987 The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Fenn, S. +5 more
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Risk factors and clinical correlates of neoplastic transformation in gastric hyperplastic polyps in Chinese patients [PDF]
, 2020 Gastric hyperplastic polyps (GHPs) have a potential risk of neoplastic transformation, but the responsible mechanisms have not yet been established. We conducted a study involving 55 patients (33 female) who had undergone endoscopic or surgical resection
Zhang, Shutian +4 more
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Neoplastic transformation of breast epithelial cells by genotoxic stress [PDF]
BMC Cancer, 2010 Abstract Background Exposure to genotoxic stresses such as radiation and tobacco smoke can cause increased cancer incidence rate as reflected in an in depth meta-analysis of data for women and breast cancer incidence.
Raman Venu +2 more
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Squamous cell carcinoma arising in ovarian mature cystic teratoma: report of three cases
Journal of Pathology of Nepal, 2012 Malignant transformation of mature cystic teratoma of the ovary is rare. A wide variety of malignant tumors may arise within benign mature cystic teratoma.
R Bashyal, MC Lee
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Malignant transformation of abdominal wall endometriosis to clear cell carcinoma: case report
São Paulo Medical Journal, 2017 BACKGROUND: Malignant transformation of endometriosis in the abdominal wall is a rare and still poorly understood event. Less than 30 cases have been reported in the worldwide literature. Most cases of solid tumors are report in a previous abdominal scar
João Kleber de Almeida Gentile +7 more
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EMBO Molecular Medicine, 2013 Initiating neoplastic cell transformation events are of paramount importance for the comprehension of regeneration and vanguard oncogenic processes but are difficult to characterize and frequently clinically overlooked.
Gonçalo Regalo, Achim Leutz
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Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. [PDF]
PLoS ONE, 2011 High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation.
Svetlana Vinokurova +1 more
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