Results 21 to 30 of about 633,194 (250)

Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells

open access: yesStem cell research & therapeutics, 2019
Mesenchymal stromal cells isolated from bone marrow (MSC) represent an attractive source of adult stem cells for regenerative medicine. However, thorough research is required into their clinical application safety issues concerning a risk of potential ...
S. Melnik   +6 more
semanticscholar   +1 more source

Squamous cell carcinoma arising in ovarian mature cystic teratoma: report of three cases

open access: yesJournal of Pathology of Nepal, 2012
Malignant transformation of mature cystic teratoma of the ovary is rare. A wide variety of malignant tumors may arise within benign mature cystic teratoma.
R Bashyal, MC Lee
doaj   +1 more source

Malignant transformation of abdominal wall endometriosis to clear cell carcinoma: case report

open access: yesSão Paulo Medical Journal, 2017
BACKGROUND: Malignant transformation of endometriosis in the abdominal wall is a rare and still poorly understood event. Less than 30 cases have been reported in the worldwide literature. Most cases of solid tumors are report in a previous abdominal scar
João Kleber de Almeida Gentile   +7 more
doaj   +1 more source

Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia

open access: yesHaematologica, 2021
Adult T-cell leukemia-lymphoma (ATL), is a highly malignant T-cell neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1), characterized by a poor prognosis.
Greta Forlani   +6 more
doaj   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

open access: yes, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D   +10 more
core   +1 more source

Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia

open access: yesEMBO Molecular Medicine, 2013
Initiating neoplastic cell transformation events are of paramount importance for the comprehension of regeneration and vanguard oncogenic processes but are difficult to characterize and frequently clinically overlooked.
Gonçalo Regalo, Achim Leutz
doaj   +1 more source

Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]

open access: yes, 2018
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core   +1 more source

Eriodictyol Inhibits RSK2-ATF1 Signaling and Suppresses EGF-induced Neoplastic Cell Transformation*

open access: yesJournal of Biological Chemistry, 2010
RSK2 is a widely expressed serine/threonine kinase, and its activation enhances cell proliferation. Here, we report that ATF1 is a novel substrate of RSK2 and that RSK2-ATF1 signaling plays an important role in EGF-induced neoplastic cell transformation.
Kangdong Liu   +11 more
semanticscholar   +1 more source

Neoplastic transformation of mouse C3H 10T1/2 and Syrian hamster embryo cells by heavy ions [PDF]

open access: yes, 1989
C3H 10T1/2 mouse-embryo fibroblasts were used for transformation experiments to study the effectiveness of various heavy ions with energies up to 20 MeV/u and LET values from 170 to 16.000 keV/μm.
A.M. Kellerer   +24 more
core   +1 more source

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype

open access: yesCell Communication and Signaling, 2023
NF-κB transcription factors are critical regulators of innate and adaptive immunity and major mediators of inflammatory signaling. The NF-κB signaling is dysregulated in a significant number of cancers and drives malignant transformation through ...
Amy Oh   +7 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy