Gonadoblastoma Arising in Undifferentiated Gonadal Tissue within Dysgenetic Gonads [PDF]
, 2006 Purpose: The purpose of the study was to define the histological origin of gonadoblastomas, allowing the identification of high-risk patients. Experimental Design: Sixty paraffin-embedded gonadectomy or gonadal biopsy samples of 43 patients with ...
Kula, Krzysztof +20 more
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Upregulation of Twist in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis [PDF]
, 2006 Background: The antiapoptotic and epithelial-mesenchymal transition activities of Twist have been implicated in the neoplastic transformation and the development of metastasis, respectively.
Wang, X +21 more
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Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. [PDF]
PLoS ONE, 2011 High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation.
Svetlana Vinokurova +1 more
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Cell Division, 2008 Mitogenic induction of cyclin D1, the allosteric regulator of CDK4/6, is a key regulatory event contributing to G1 phase progression. Following the G1/S transition, cyclin D1 activation is antagonized by GSK3β-dependent threonine-286 (Thr-286 ...
Diehl J Alan, Pontano Laura L
doaj +1 more source
Bladder Cancer, 2020 BACKGROUND: Androgen receptor (AR) activation has been implicated in the pathogenesis of urothelial cancer. However, it remains controversial whether 5α-reductase inhibitors (5α-RIs), which are known for blocking the conversion of testosterone to the ...
Yujiro Nagata +4 more
doaj +1 more source
Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report
Dermatology Reports, 2021 Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical regions.
Walter Belda Jr. +3 more
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Metabolic Plasticity of Tumor Cell Mitochondria
Frontiers in Oncology, 2018 Mitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell.
Giuseppe Cannino +4 more
doaj +1 more source
Risk factors and clinical correlates of neoplastic transformation in gastric hyperplastic polyps in Chinese patients [PDF]
, 2020 Gastric hyperplastic polyps (GHPs) have a potential risk of neoplastic transformation, but the responsible mechanisms have not yet been established. We conducted a study involving 55 patients (33 female) who had undergone endoscopic or surgical resection
Pritchard, DM +4 more
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Hepatocellular carcinoma arising in a telangiectatic hepatocellular adenoma
Annals of Hepatology, 2013 Telangiectatic hepatocellular adenoma is a rare, recently recognized subtype of benign liver tumor that may very rarely undergo transformation into hepatocellular carcinoma.
María Fernanda González-Lara +4 more
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Spectrum of Sinonasal Lesions with Expression of p16 and Ki-67 in Premalignant Lesions and Squamous Cell Carcinomas [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Sinonasal masses are heterogeneous group of non-neoplastic and neoplastic lesions originating from epithelial, mesenchymal, haematolymphoid and neuroendocrine cells.
Madhumita Paul +3 more
doaj +1 more source