Results 21 to 30 of about 292,678 (265)
Cell Division, 2008 Mitogenic induction of cyclin D1, the allosteric regulator of CDK4/6, is a key regulatory event contributing to G1 phase progression. Following the G1/S transition, cyclin D1 activation is antagonized by GSK3β-dependent threonine-286 (Thr-286 ...
Diehl J Alan, Pontano Laura L
doaj +1 more source
Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report
Dermatology Reports, 2021 Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical regions.
Walter Belda Jr. +3 more
doaj +1 more source
Metabolic Plasticity of Tumor Cell Mitochondria
Frontiers in Oncology, 2018 Mitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell.
Giuseppe Cannino +4 more
doaj +1 more source
Hepatocellular carcinoma arising in a telangiectatic hepatocellular adenoma
Annals of Hepatology, 2013 Telangiectatic hepatocellular adenoma is a rare, recently recognized subtype of benign liver tumor that may very rarely undergo transformation into hepatocellular carcinoma.
María Fernanda González-Lara +4 more
doaj +1 more source
Spectrum of Sinonasal Lesions with Expression of p16 and Ki-67 in Premalignant Lesions and Squamous Cell Carcinomas [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Sinonasal masses are heterogeneous group of non-neoplastic and neoplastic lesions originating from epithelial, mesenchymal, haematolymphoid and neuroendocrine cells.
Madhumita Paul +3 more
doaj +1 more source
STEPS IN THE NEOPLASTIC TRANSFORMATION OF HAMSTER EMBRYO CELLS BY POLYOMA VIRUS [PDF]
Proceedings of the National Academy of Sciences, 1963 Cultures of hamster embryo cells infected with polyoma virus undergo a characteristic transformation within several weeks after infection. The transformed cultures are constituted by highly atypical cells which have an abnormal morphology, grow rapidly in vitro, and give rise to progressively growing tumors when inoculated subcutaneously into the adult
Vogt, Marguerite, Dulbecco, Renato
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa +7 more
wiley +1 more source
PLoS ONE, 2014 The leucine rich repeats and immunoglobulin-like protein 1 (LRIG1) is a newly discovered negative regulator of epidermal growth factor receptor (EGFR) and a proposed tumor suppressor.
Maho Nagata +5 more
doaj +1 more source
Temporal dissection of K-ras(G12D) mutant in vitro and in vivo using a regulatable K-ras(G12D) mouse allele. [PDF]
PLoS ONE, 2012 Animal models which allow the temporal regulation of gene activities are valuable for dissecting gene function in tumorigenesis. Here we have constructed a conditional inducible estrogen receptor-K-ras(G12D) (ER-K-ras(G12D)) knock-in mice allele that ...
Zuoyun Wang +5 more
doaj +1 more source
Nowotwory, 2022 The primary function of intracellular heat shock proteins (HSPs) is to protect the cell by suppressing the effects of various stress factors by either refolding misfolded proteins or blocking apoptosis. After neoplastic transformation, cells overexpress
Iryna Boliukh +2 more
doaj +1 more source