Results 181 to 190 of about 593,168 (347)

Dysbiosis-Mediated Regulation of Stem Cells the First Hit for Cancer Generation. [PDF]

Int J Mol Sci
Gargiulo-Isacco C, Pham VH, Nguyen KCD, Tran TC, Aityan SK, Del Prete R, Jirillo E, Santacroce L.   +7 more
europepmc   +1 more source

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

Leukemia, 2003
F. Chang, John T. Lee, P. Navolanic, Linda S. Steelman, J. G. Shelton, W. Blalock, R. Franklin, J. McCubrey   +7 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Case Report: Testicular teratoma with malignant transformation to melanoma and concurrent metastatic carcinoma of undetermined primary origin in a red deer (<i>Cervus elaphus</i>). [PDF]

Front Vet Sci
Criado M, Prieto P, Palomares JJ, Lopezosa D, Zapico D, Mendívil P, Benavides J, Ferreras MC, Espinosa J.   +8 more
europepmc   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source

Histomorphological development and progression of gastric intramucosal papillary adenocarcinoma-a retrospective study. [PDF]

Front Oncol
Wang YK, Zou XF, Wang WY, Li YY, Zhong Y, Guo P, Wang T, Xu SL, Wang SN.   +8 more
europepmc   +1 more source

Cutaneous Tuberculosis in the Modern Era: A Case of Lupus Vulgaris with Surgical Management and a Review of Clinical Spectrum, Diagnostic Challenges, and Malignant Potential. [PDF]

J Clin Med
Knecht-Gurwin K, Chlebicka I, Matusiak L, Woźniak Z, Bieniek A, Szepietowski JC.   +5 more
europepmc   +1 more source

CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.

Cancer Research, 2013
Shuping Yang, Lin Zhang, Miao Liu, Rong Chong, Shi-jian Ding, Yuanhong Chen, Jixin Dong   +6 more
semanticscholar   +1 more source

Mechanisms of Viral Oncogenesis: DNA and RNA Viruses in Human Cancer. [PDF]

J Inflamm Res
Yao N, Huang B.
europepmc   +1 more source

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Proceedings of the National Academy of Sciences of the United States of America, 2003
C. Kleer, Q. Cao, S. Varambally, R. Shen, I. Ota, S. Tomlins, D. Ghosh, R. Sewalt, A. Otte, D. Hayes, M. Sabel, D. Livant, S. Weiss, M. Rubin, A. Chinnaiyan   +14 more
semanticscholar   +1 more source