Results 1 to 10 of about 186,234 (266)
Oncogenic viruses and their role in tumor formation [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2005 Oncogenic viruses trigger persistent infections, which can stimulate uncontrolled cell growth by inducing cell transformation. Different oncogenic viruses use different mechanisms for infecting cells.
Ćupić Maja +2 more
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Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes
Viruses, 2021 The adenovirus type 5 (HAdV-C5) E1 transcription unit encodes regulatory proteins that are essential for viral replication and transformation. Among these, E1A and E1B-55K act as key multifunctional HAdV-C5 proteins involved in various steps of the viral
Wing-Hang Ip +8 more
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The Role of microRNAs, Long Non-coding RNAs, and Circular RNAs in Cervical Cancer
Frontiers in Oncology, 2020 Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and constitutive expression of viral oncogenes have been recognized as the main cause of the complex molecular changes leading to transformation of cervical epithelial cells.
Maria Lina Tornesello +8 more
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The eEF1A proteins: at the crossroads of oncogenesis, apoptosis and viral infections.
Frontiers in Oncology, 2015 Eukaryotic translation elongation factors 1 alpha, eEF1A1 and eEF1A2, are not only translation factors, but also pleiotropic proteins that are highly expressed in human tumors, including breast cancer, ovarian cancer and lung cancer.
Georges eHerbein +2 more
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Liver Cell Transformation in Chronic HBV Infection
Viruses, 2009 Epidemiological studies have provided overwhelming evidence for a causal role of chronic HBV infection in the development of hepatocellular carcinoma (HCC), but the molecular mechanisms underlying virally-induced tumorigenesis remain largely debated.
Marie Annick Buendia +3 more
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In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ.
PLoS Pathogens, 2021 Adult T cell leukemia (ATL) is an aggressive malignancy secondary to chronic infection by the human T-cell leukemia virus type 1 (HTLV-1) infection. Two viral proteins, Tax and HBZ, play central roles in ATL leukemogenesis.
Abdou Akkouche +6 more
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Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. [PDF]
PLoS Biology, 2005 DNA viruses such as herpesviruses are known to encode homologs of cellular antiapoptotic viral Bcl-2 proteins (vBcl-2s), which protect the virus from apoptosis in its host cell during virus synthesis.
Markus Altmann, Wolfgang Hammerschmidt
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Viral DNA in Polyoma- and SV40-Transformed Cell Lines [PDF]
Proceedings of the National Academy of Sciences, 1968 It is clear that cells transformed by the small DNA-containing viruses, polyoma virus (Py) and SV40, harbor the viral DNA since they contain viral mRNA,1 and some lines even yield infectious virus after fusion with cells able to support the multiplication of the virus.2, 3 Very little is known, however, about the state of the viral DNA in these cells ...
H, Westphal, R, Dulbecco
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Papillomavirus Research, 2018 Canine oral papillomavirus (CPV1, also known as COPV), the most common cause of non-neoplastic papillomas, has not been shown to cause squamous cell carcinomas (SCC).
Tuddow Thaiwong +5 more
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Viral genome integration of canine papillomavirus 16
Papillomavirus Research, 2019 Papillomaviruses infect humans and animals, most often causing benign proliferations on skin or mucosal surfaces. Rarely, these infections persist and progress to cancer.
Jennifer Luff +5 more
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